Zinc complexes as fluorescent chemosensors for nucleic acids: New perspectives for a "boring" element

Anna Maria Almerico, Antonino Lauria, Alessio Terenzi, Giampaolo Barone, Antonino Lauria, Anna Maria Almerico, Alessio Terenzi, Giampaolo Barone

Risultato della ricerca: Articlepeer review

20 Citazioni (Scopus)

Abstract

Zinc(ii) complexes are effective and selective nucleic acid-binders and strongly fluorescent molecules in the low energy range, from the visible to the near infrared. These two properties have often been exploited to quantitatively detect nucleic acids in biological samples, in both in vitro and in vivo models. In particular, the fluorescent emission of several zinc(ii) complexes is drastically enhanced or quenched by the binding to nucleic acids and/or upon visible light exposure, in a different fashion in bulk solution and when bound to DNA. The twofold objective of this perspective is (1) to review recent utilisations of zinc(ii) complexes as selective fluorescent probes for nucleic acids and (2) to highlight their novel potential applications as diagnostic tools based on their photophysical properties. This journal is
Lingua originaleEnglish
pagine (da-a)3527-3535
Numero di pagine9
RivistaDALTON TRANSACTIONS
Volume44
Stato di pubblicazionePublished - 2015

All Science Journal Classification (ASJC) codes

  • Inorganic Chemistry

Fingerprint Entra nei temi di ricerca di 'Zinc complexes as fluorescent chemosensors for nucleic acids: New perspectives for a "boring" element'. Insieme formano una fingerprint unica.

Cita questo