Xyloglucan-based hydrogel films for wound dressing: Structure-property relationships

Clelia Dispenza, Maria Antonietta Sabatino, Alessia Ajovalasit, Sabina Alessi, Pasquale Picone, Clelia Dispenza, Daniela Giacomazza, Marta Di Carlo, Marta Di Carlo, Pasquale Picone

Risultato della ricerca: Articlepeer review

48 Citazioni (Scopus)


Thin xyloglucan-based hydrogel films have been synthetized and characterized in the prospect of producing wound dressings. Polyvinyl alcohol (PVA) and glycerol (Gro) were added to have an optimal combination of softness, conformability and resilience. Physical hydrogels have been transformed into permanent covalent hydrogels by reaction with glutaraldehyde (GA). Network structure-process-property relationships are discussed on the account of the results of several complementary characterizations: FTIR, rheology, thermal analysis, morphological analysis, moisture retention and swelling measurements. Selected formulations were also subjected to preliminary in vitro cytotoxicity tests. The physical and mechanical properties of some of the xyloglucan-based hydrogel films produced, combined with absence of cytotoxicity, make them suitable candidates for integration with sensors to monitor the wound healing process and further biological investigations in animal models.
Lingua originaleEnglish
pagine (da-a)262-272
Numero di pagine11
RivistaCarbohydrate Polymers
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.2500.2507???
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