Waterborne Norovirus outbreak at a seaside resort likely originating from municipal water distribution system failure

Giovanni Giammanco, Simona De Grazia, Giuseppa Purpari, Floriana Bonura, Noemi Urone, Vincenzo Cappa, Giuseppa Purpari, Annalisa Guercio, Angelo Marino, Ilaria Di Bartolo, Mandolfo, Saglimbene, Cuccia

Risultato della ricerca: Article

3 Citazioni (Scopus)

Abstract

In May 2016 a Norovirus (NoV) gastroenteritis outbreak involved a high school class visiting a seaside resort near Taormina (Mascali, Sicily). Twenty-four students and a teacher were affected and 17 of them showed symptoms on the second day of the journey, while the others got ill within the following 2 days. Symptoms included vomiting, diarrhoea and fever, and 12 students required hospitalisation. Stool samples tested positive for NoV genome by Real-Time polymerase chain reaction assay in all 25 symptomatic subjects. The GII.P2/GII.2 NoV genotype was linked to the outbreak by ORF1/ORF2 sequence analysis. The epidemiological features of the outbreak were consistent with food/waterborne followed by person-to-person and/or vomit transmission. Food consumed at a shared lunch on the first day of the trip was associated to illness and drinking un-bottled tap water was also considered as a risk factor. The analysis of water samples revealed the presence of bacterial indicators of faecal contamination in the water used in the resort as well as in other areas of the municipal water network, linking the NoV gastroenteritis outbreak to tap water pollution from sewage leakage. From a single water sample, an amplicon whose sequence corresponded to the capsid genotype recovered from patients could be obtained.
Lingua originaleEnglish
pagine (da-a)879-887
Numero di pagine9
RivistaEpidemiology and Infection
Volume146
Stato di pubblicazionePublished - 2018

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Norovirus
Disease Outbreaks
Water
Gastroenteritis
Genotype
Sicily
Students
Water Pollution
Food
Lunch
Capsid
Sewage
Drinking Water
Drinking
Vomiting
Sequence Analysis
Real-Time Polymerase Chain Reaction
Diarrhea
Hospitalization
Fever

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Infectious Diseases

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Waterborne Norovirus outbreak at a seaside resort likely originating from municipal water distribution system failure. / Giammanco, Giovanni; De Grazia, Simona; Purpari, Giuseppa; Bonura, Floriana; Urone, Noemi; Cappa, Vincenzo; Purpari, Giuseppa; Guercio, Annalisa; Marino, Angelo; Di Bartolo, Ilaria; Mandolfo; Saglimbene; Cuccia.

In: Epidemiology and Infection, Vol. 146, 2018, pag. 879-887.

Risultato della ricerca: Article

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title = "Waterborne Norovirus outbreak at a seaside resort likely originating from municipal water distribution system failure",
abstract = "In May 2016 a Norovirus (NoV) gastroenteritis outbreak involved a high school class visiting a seaside resort near Taormina (Mascali, Sicily). Twenty-four students and a teacher were affected and 17 of them showed symptoms on the second day of the journey, while the others got ill within the following 2 days. Symptoms included vomiting, diarrhoea and fever, and 12 students required hospitalisation. Stool samples tested positive for NoV genome by Real-Time polymerase chain reaction assay in all 25 symptomatic subjects. The GII.P2/GII.2 NoV genotype was linked to the outbreak by ORF1/ORF2 sequence analysis. The epidemiological features of the outbreak were consistent with food/waterborne followed by person-to-person and/or vomit transmission. Food consumed at a shared lunch on the first day of the trip was associated to illness and drinking un-bottled tap water was also considered as a risk factor. The analysis of water samples revealed the presence of bacterial indicators of faecal contamination in the water used in the resort as well as in other areas of the municipal water network, linking the NoV gastroenteritis outbreak to tap water pollution from sewage leakage. From a single water sample, an amplicon whose sequence corresponded to the capsid genotype recovered from patients could be obtained.",
author = "Giovanni Giammanco and {De Grazia}, Simona and Giuseppa Purpari and Floriana Bonura and Noemi Urone and Vincenzo Cappa and Giuseppa Purpari and Annalisa Guercio and Angelo Marino and {Di Bartolo}, Ilaria and Mandolfo and Saglimbene and Cuccia",
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T1 - Waterborne Norovirus outbreak at a seaside resort likely originating from municipal water distribution system failure

AU - Giammanco, Giovanni

AU - De Grazia, Simona

AU - Purpari, Giuseppa

AU - Bonura, Floriana

AU - Urone, Noemi

AU - Cappa, Vincenzo

AU - Purpari, Giuseppa

AU - Guercio, Annalisa

AU - Marino, Angelo

AU - Di Bartolo, Ilaria

AU - Mandolfo, null

AU - Saglimbene, null

AU - Cuccia, null

PY - 2018

Y1 - 2018

N2 - In May 2016 a Norovirus (NoV) gastroenteritis outbreak involved a high school class visiting a seaside resort near Taormina (Mascali, Sicily). Twenty-four students and a teacher were affected and 17 of them showed symptoms on the second day of the journey, while the others got ill within the following 2 days. Symptoms included vomiting, diarrhoea and fever, and 12 students required hospitalisation. Stool samples tested positive for NoV genome by Real-Time polymerase chain reaction assay in all 25 symptomatic subjects. The GII.P2/GII.2 NoV genotype was linked to the outbreak by ORF1/ORF2 sequence analysis. The epidemiological features of the outbreak were consistent with food/waterborne followed by person-to-person and/or vomit transmission. Food consumed at a shared lunch on the first day of the trip was associated to illness and drinking un-bottled tap water was also considered as a risk factor. The analysis of water samples revealed the presence of bacterial indicators of faecal contamination in the water used in the resort as well as in other areas of the municipal water network, linking the NoV gastroenteritis outbreak to tap water pollution from sewage leakage. From a single water sample, an amplicon whose sequence corresponded to the capsid genotype recovered from patients could be obtained.

AB - In May 2016 a Norovirus (NoV) gastroenteritis outbreak involved a high school class visiting a seaside resort near Taormina (Mascali, Sicily). Twenty-four students and a teacher were affected and 17 of them showed symptoms on the second day of the journey, while the others got ill within the following 2 days. Symptoms included vomiting, diarrhoea and fever, and 12 students required hospitalisation. Stool samples tested positive for NoV genome by Real-Time polymerase chain reaction assay in all 25 symptomatic subjects. The GII.P2/GII.2 NoV genotype was linked to the outbreak by ORF1/ORF2 sequence analysis. The epidemiological features of the outbreak were consistent with food/waterborne followed by person-to-person and/or vomit transmission. Food consumed at a shared lunch on the first day of the trip was associated to illness and drinking un-bottled tap water was also considered as a risk factor. The analysis of water samples revealed the presence of bacterial indicators of faecal contamination in the water used in the resort as well as in other areas of the municipal water network, linking the NoV gastroenteritis outbreak to tap water pollution from sewage leakage. From a single water sample, an amplicon whose sequence corresponded to the capsid genotype recovered from patients could be obtained.

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