Vitamin K deficiency bleeding leading to a diagnosis of Crohn’s Disease

Marcello Ciaccio, Giulia Bivona, Antonietta Caruso, Chiara Bellia, Bruna Lo Sasso, Luisa Agnello, Mariasanta Napolitano, Silvana Vitale, Lucio Lo Coco, Marcello Ciaccio, Mariasanta Napolitano, Rossella Gnoffo, Felicia Coraci, Filippa Bonura

Risultato della ricerca: Article

4 Citazioni (Scopus)

Abstract

We report the case of a 45 year old man who came to Emergency Room of Polyclinic for sudden onset of localized ecchymosis and widespread hematomas. He was subjected to blood count and first level investigations to assess coagulation. Based on the results, second level investigations were performed. Endoscopy of the gastrointestinal tract with histological examination revealed a diagnosis of Crohn's disease. Vitamin K deficiency causes the formation of vitamin K-dependent clotting factors that cannot perform their pro-coagulant action. Consequently, patients present with hemorrhagic manifestations. Clinical and laboratory features observed in this patient show that the deficiency of vitamin K-dependent coagulation factors may reveal a complex clinical condition such as an inflammatory bowel disease.
Lingua originaleEnglish
pagine (da-a)-
Numero di pagine4
RivistaAnnals of Clinical and Laboratory Science
Volume44
Stato di pubblicazionePublished - 2014

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Vitamin K Deficiency Bleeding
Vitamin K Deficiency
Blood Coagulation Factors
Vitamin K
Crohn Disease
Ecchymosis
Coagulants
Emergency rooms
Inflammatory Bowel Diseases
Hematoma
Endoscopy
Gastrointestinal Tract
Hospital Emergency Service
Coagulation
Blood

All Science Journal Classification (ASJC) codes

  • Immunology and Allergy
  • Medical Laboratory Technology
  • Clinical Biochemistry
  • Molecular Biology
  • Hematology
  • Immunology
  • Pathology and Forensic Medicine
  • Microbiology

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Vitamin K deficiency bleeding leading to a diagnosis of Crohn’s Disease. / Ciaccio, Marcello; Bivona, Giulia; Caruso, Antonietta; Bellia, Chiara; Lo Sasso, Bruna; Agnello, Luisa; Napolitano, Mariasanta; Vitale, Silvana; Coco, Lucio Lo; Ciaccio, Marcello; Napolitano, Mariasanta; Gnoffo, Rossella; Coraci, Felicia; Bonura, Filippa.

In: Annals of Clinical and Laboratory Science, Vol. 44, 2014, pag. -.

Risultato della ricerca: Article

Ciaccio, Marcello ; Bivona, Giulia ; Caruso, Antonietta ; Bellia, Chiara ; Lo Sasso, Bruna ; Agnello, Luisa ; Napolitano, Mariasanta ; Vitale, Silvana ; Coco, Lucio Lo ; Ciaccio, Marcello ; Napolitano, Mariasanta ; Gnoffo, Rossella ; Coraci, Felicia ; Bonura, Filippa. / Vitamin K deficiency bleeding leading to a diagnosis of Crohn’s Disease. In: Annals of Clinical and Laboratory Science. 2014 ; Vol. 44. pagg. -.
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abstract = "We report the case of a 45 year old man who came to Emergency Room of Polyclinic for sudden onset of localized ecchymosis and widespread hematomas. He was subjected to blood count and first level investigations to assess coagulation. Based on the results, second level investigations were performed. Endoscopy of the gastrointestinal tract with histological examination revealed a diagnosis of Crohn's disease. Vitamin K deficiency causes the formation of vitamin K-dependent clotting factors that cannot perform their pro-coagulant action. Consequently, patients present with hemorrhagic manifestations. Clinical and laboratory features observed in this patient show that the deficiency of vitamin K-dependent coagulation factors may reveal a complex clinical condition such as an inflammatory bowel disease.",
author = "Marcello Ciaccio and Giulia Bivona and Antonietta Caruso and Chiara Bellia and {Lo Sasso}, Bruna and Luisa Agnello and Mariasanta Napolitano and Silvana Vitale and Coco, {Lucio Lo} and Marcello Ciaccio and Mariasanta Napolitano and Rossella Gnoffo and Felicia Coraci and Filippa Bonura",
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T1 - Vitamin K deficiency bleeding leading to a diagnosis of Crohn’s Disease

AU - Ciaccio, Marcello

AU - Bivona, Giulia

AU - Caruso, Antonietta

AU - Bellia, Chiara

AU - Lo Sasso, Bruna

AU - Agnello, Luisa

AU - Napolitano, Mariasanta

AU - Vitale, Silvana

AU - Coco, Lucio Lo

AU - Ciaccio, Marcello

AU - Napolitano, Mariasanta

AU - Gnoffo, Rossella

AU - Coraci, Felicia

AU - Bonura, Filippa

PY - 2014

Y1 - 2014

N2 - We report the case of a 45 year old man who came to Emergency Room of Polyclinic for sudden onset of localized ecchymosis and widespread hematomas. He was subjected to blood count and first level investigations to assess coagulation. Based on the results, second level investigations were performed. Endoscopy of the gastrointestinal tract with histological examination revealed a diagnosis of Crohn's disease. Vitamin K deficiency causes the formation of vitamin K-dependent clotting factors that cannot perform their pro-coagulant action. Consequently, patients present with hemorrhagic manifestations. Clinical and laboratory features observed in this patient show that the deficiency of vitamin K-dependent coagulation factors may reveal a complex clinical condition such as an inflammatory bowel disease.

AB - We report the case of a 45 year old man who came to Emergency Room of Polyclinic for sudden onset of localized ecchymosis and widespread hematomas. He was subjected to blood count and first level investigations to assess coagulation. Based on the results, second level investigations were performed. Endoscopy of the gastrointestinal tract with histological examination revealed a diagnosis of Crohn's disease. Vitamin K deficiency causes the formation of vitamin K-dependent clotting factors that cannot perform their pro-coagulant action. Consequently, patients present with hemorrhagic manifestations. Clinical and laboratory features observed in this patient show that the deficiency of vitamin K-dependent coagulation factors may reveal a complex clinical condition such as an inflammatory bowel disease.

UR - http://hdl.handle.net/10447/98445

M3 - Article

VL - 44

SP - -

JO - Annals of Clinical and Laboratory Science

JF - Annals of Clinical and Laboratory Science

SN - 0091-7370

ER -