Visceral obesity and metabolic syndrome: two faces of the same medal?

Cariello, T

Risultato della ricerca: Article

46 Citazioni (Scopus)

Abstract

In this review, we have analyzed the role of visceral obesity in the occurrence of metabolic syndrome (MetS). MetS is a common metabolic disorder that has been related recently to the increasing prevalence of obesity. The disorder is defined in various ways, but in the near future a new definition(s) should be applicable worldwide. The pathophysiology has been largely attributed, in the past years, to insulin resistance, although several epidemiological and pathophysiological data now indicate visceral obesity as a main factor in the occurrence of all the components of MetS. In view of this, relationships among visceral obesity, free fatty acids, dyslipidemia and insulin resistance have been reported. In addition, the effects of some adipocytokines and other proinflammatory factors produced by fat accumulation on the occurrence of MetS have been also emphasized. Accordingly, the "hypoadiponectinemia hypothesis" has been proposed as the most interesting to explain the pathophysiology of MetS. The epidemiologic, pathophysiologic and clinical data reported seem to indicate that MetS might be considered a fatal consequence of visceral obesity.
Lingua originaleEnglish
pagine (da-a)-
Numero di pagine9
RivistaInternal and Emergency Medicine
Volume2009-12-09
Stato di pubblicazionePublished - 2009

Fingerprint

Numismatics
Abdominal Obesity
Insulin Resistance
Adipokines
Dyslipidemias
Nonesterified Fatty Acids
Obesity
Fats

All Science Journal Classification (ASJC) codes

  • Emergency Medicine
  • Internal Medicine

Cita questo

Visceral obesity and metabolic syndrome: two faces of the same medal? / Cariello, T.

In: Internal and Emergency Medicine, Vol. 2009-12-09, 2009, pag. -.

Risultato della ricerca: Article

@article{23e792d432884171bd34848c27f3e031,
title = "Visceral obesity and metabolic syndrome: two faces of the same medal?",
abstract = "In this review, we have analyzed the role of visceral obesity in the occurrence of metabolic syndrome (MetS). MetS is a common metabolic disorder that has been related recently to the increasing prevalence of obesity. The disorder is defined in various ways, but in the near future a new definition(s) should be applicable worldwide. The pathophysiology has been largely attributed, in the past years, to insulin resistance, although several epidemiological and pathophysiological data now indicate visceral obesity as a main factor in the occurrence of all the components of MetS. In view of this, relationships among visceral obesity, free fatty acids, dyslipidemia and insulin resistance have been reported. In addition, the effects of some adipocytokines and other proinflammatory factors produced by fat accumulation on the occurrence of MetS have been also emphasized. Accordingly, the {"}hypoadiponectinemia hypothesis{"} has been proposed as the most interesting to explain the pathophysiology of MetS. The epidemiologic, pathophysiologic and clinical data reported seem to indicate that MetS might be considered a fatal consequence of visceral obesity.",
keywords = "Metabolic syndrome - Visceral obesity - Adipocytokines - Adiponectin",
author = "{Cariello, T} and Giuseppe Licata and Rosario Scaglione and {Di Chiara}, Tiziana",
year = "2009",
language = "English",
volume = "2009-12-09",
pages = "--",
journal = "Internal and Emergency Medicine",
issn = "1828-0447",
publisher = "Springer-Verlag Italia",

}

TY - JOUR

T1 - Visceral obesity and metabolic syndrome: two faces of the same medal?

AU - Cariello, T

AU - Licata, Giuseppe

AU - Scaglione, Rosario

AU - Di Chiara, Tiziana

PY - 2009

Y1 - 2009

N2 - In this review, we have analyzed the role of visceral obesity in the occurrence of metabolic syndrome (MetS). MetS is a common metabolic disorder that has been related recently to the increasing prevalence of obesity. The disorder is defined in various ways, but in the near future a new definition(s) should be applicable worldwide. The pathophysiology has been largely attributed, in the past years, to insulin resistance, although several epidemiological and pathophysiological data now indicate visceral obesity as a main factor in the occurrence of all the components of MetS. In view of this, relationships among visceral obesity, free fatty acids, dyslipidemia and insulin resistance have been reported. In addition, the effects of some adipocytokines and other proinflammatory factors produced by fat accumulation on the occurrence of MetS have been also emphasized. Accordingly, the "hypoadiponectinemia hypothesis" has been proposed as the most interesting to explain the pathophysiology of MetS. The epidemiologic, pathophysiologic and clinical data reported seem to indicate that MetS might be considered a fatal consequence of visceral obesity.

AB - In this review, we have analyzed the role of visceral obesity in the occurrence of metabolic syndrome (MetS). MetS is a common metabolic disorder that has been related recently to the increasing prevalence of obesity. The disorder is defined in various ways, but in the near future a new definition(s) should be applicable worldwide. The pathophysiology has been largely attributed, in the past years, to insulin resistance, although several epidemiological and pathophysiological data now indicate visceral obesity as a main factor in the occurrence of all the components of MetS. In view of this, relationships among visceral obesity, free fatty acids, dyslipidemia and insulin resistance have been reported. In addition, the effects of some adipocytokines and other proinflammatory factors produced by fat accumulation on the occurrence of MetS have been also emphasized. Accordingly, the "hypoadiponectinemia hypothesis" has been proposed as the most interesting to explain the pathophysiology of MetS. The epidemiologic, pathophysiologic and clinical data reported seem to indicate that MetS might be considered a fatal consequence of visceral obesity.

KW - Metabolic syndrome - Visceral obesity - Adipocytokines - Adiponectin

UR - http://hdl.handle.net/10447/49214

M3 - Article

VL - 2009-12-09

SP - -

JO - Internal and Emergency Medicine

JF - Internal and Emergency Medicine

SN - 1828-0447

ER -