Validity of the study of sentinel lymph nodes in the treatment of breast carcinoma.

Vieni S; Cipolla C; Fricano S; Amato C; Graceffa G; Sandonato L; Prinzi G; Latteri S; Latteri M

Risultato della ricerca: Article

1 Citazione (Scopus)

Abstract

Since it was introduced in the 1990s, axillary sentinel lymph-node biopsy has been rapidly and widely adopted to avoid complete axillary dissection (though this is still the standard procedure). The aims of the study were two-fold: (i) to determine the value of different techniques of sentinel lymph-node identification and (ii) to verify the predictive value of such procedures through histological examination of the sentinel lymph node and axillary dissection in the same patients. Both sentinel lymph-node biopsy and axillary dissection were performed in 230 patients with T1 and T2 (< 3 cm) carcinoma of the breast. Preoperative lymphoscintigraphy was able to identify the sentinel lymph node in 97.4% of cases, but, with an intraoperative hand-held probe, it was possible to find the sentinel lymph node in 98.2% of cases (226/230 patients). The sentinel lymph node was metastatic in 49.1% of cases (111/226 patients) and negative in 50.9% (115/226). The incidence of false-negative cases was 2.6% (2/115 patients). The predictive value of the sentinel lymph node was 98.7%. Finally, lymph-mode mapping is possible is a very high percentage of patients and therefore it is always advisable to use all three methods of identification together. The diagnostic reliability of sentinel lymph-node status is equally high. At present there no studies are available with a long-term follow-up to confirm these findings, and therefore axillary dissection is still the standard surgical treatment for breast cancer.
Lingua originaleEnglish
pagine (da-a)215-222
Numero di pagine8
RivistaChirurgia Italiana
Volume56(2)
Stato di pubblicazionePublished - 2004

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Breast Neoplasms
Dissection
Sentinel Lymph Node Biopsy
Therapeutics
Lymphoscintigraphy
Lymph
Sentinel Lymph Node
Lymph Node Excision
Hand
Incidence

All Science Journal Classification (ASJC) codes

  • Surgery

Cita questo

Vieni S; Cipolla C; Fricano S; Amato C; Graceffa G; Sandonato L; Prinzi G; Latteri S; Latteri M (2004). Validity of the study of sentinel lymph nodes in the treatment of breast carcinoma. Chirurgia Italiana, 56(2), 215-222.

Validity of the study of sentinel lymph nodes in the treatment of breast carcinoma. / Vieni S; Cipolla C; Fricano S; Amato C; Graceffa G; Sandonato L; Prinzi G; Latteri S; Latteri M.

In: Chirurgia Italiana, Vol. 56(2), 2004, pag. 215-222.

Risultato della ricerca: Article

Vieni S; Cipolla C; Fricano S; Amato C; Graceffa G; Sandonato L; Prinzi G; Latteri S; Latteri M 2004, 'Validity of the study of sentinel lymph nodes in the treatment of breast carcinoma.', Chirurgia Italiana, vol. 56(2), pagg. 215-222.
Vieni S; Cipolla C; Fricano S; Amato C; Graceffa G; Sandonato L; Prinzi G; Latteri S; Latteri M. Validity of the study of sentinel lymph nodes in the treatment of breast carcinoma. Chirurgia Italiana. 2004;56(2):215-222.
Vieni S; Cipolla C; Fricano S; Amato C; Graceffa G; Sandonato L; Prinzi G; Latteri S; Latteri M. / Validity of the study of sentinel lymph nodes in the treatment of breast carcinoma. In: Chirurgia Italiana. 2004 ; Vol. 56(2). pagg. 215-222.
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abstract = "Since it was introduced in the 1990s, axillary sentinel lymph-node biopsy has been rapidly and widely adopted to avoid complete axillary dissection (though this is still the standard procedure). The aims of the study were two-fold: (i) to determine the value of different techniques of sentinel lymph-node identification and (ii) to verify the predictive value of such procedures through histological examination of the sentinel lymph node and axillary dissection in the same patients. Both sentinel lymph-node biopsy and axillary dissection were performed in 230 patients with T1 and T2 (< 3 cm) carcinoma of the breast. Preoperative lymphoscintigraphy was able to identify the sentinel lymph node in 97.4{\%} of cases, but, with an intraoperative hand-held probe, it was possible to find the sentinel lymph node in 98.2{\%} of cases (226/230 patients). The sentinel lymph node was metastatic in 49.1{\%} of cases (111/226 patients) and negative in 50.9{\%} (115/226). The incidence of false-negative cases was 2.6{\%} (2/115 patients). The predictive value of the sentinel lymph node was 98.7{\%}. Finally, lymph-mode mapping is possible is a very high percentage of patients and therefore it is always advisable to use all three methods of identification together. The diagnostic reliability of sentinel lymph-node status is equally high. At present there no studies are available with a long-term follow-up to confirm these findings, and therefore axillary dissection is still the standard surgical treatment for breast cancer.",
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T1 - Validity of the study of sentinel lymph nodes in the treatment of breast carcinoma.

AU - Vieni S; Cipolla C; Fricano S; Amato C; Graceffa G; Sandonato L; Prinzi G; Latteri S; Latteri M

AU - Latteri, Mario

AU - Vieni, Salvatore

AU - Prinzi, Gabriele

AU - Cipolla, Calogero

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N2 - Since it was introduced in the 1990s, axillary sentinel lymph-node biopsy has been rapidly and widely adopted to avoid complete axillary dissection (though this is still the standard procedure). The aims of the study were two-fold: (i) to determine the value of different techniques of sentinel lymph-node identification and (ii) to verify the predictive value of such procedures through histological examination of the sentinel lymph node and axillary dissection in the same patients. Both sentinel lymph-node biopsy and axillary dissection were performed in 230 patients with T1 and T2 (< 3 cm) carcinoma of the breast. Preoperative lymphoscintigraphy was able to identify the sentinel lymph node in 97.4% of cases, but, with an intraoperative hand-held probe, it was possible to find the sentinel lymph node in 98.2% of cases (226/230 patients). The sentinel lymph node was metastatic in 49.1% of cases (111/226 patients) and negative in 50.9% (115/226). The incidence of false-negative cases was 2.6% (2/115 patients). The predictive value of the sentinel lymph node was 98.7%. Finally, lymph-mode mapping is possible is a very high percentage of patients and therefore it is always advisable to use all three methods of identification together. The diagnostic reliability of sentinel lymph-node status is equally high. At present there no studies are available with a long-term follow-up to confirm these findings, and therefore axillary dissection is still the standard surgical treatment for breast cancer.

AB - Since it was introduced in the 1990s, axillary sentinel lymph-node biopsy has been rapidly and widely adopted to avoid complete axillary dissection (though this is still the standard procedure). The aims of the study were two-fold: (i) to determine the value of different techniques of sentinel lymph-node identification and (ii) to verify the predictive value of such procedures through histological examination of the sentinel lymph node and axillary dissection in the same patients. Both sentinel lymph-node biopsy and axillary dissection were performed in 230 patients with T1 and T2 (< 3 cm) carcinoma of the breast. Preoperative lymphoscintigraphy was able to identify the sentinel lymph node in 97.4% of cases, but, with an intraoperative hand-held probe, it was possible to find the sentinel lymph node in 98.2% of cases (226/230 patients). The sentinel lymph node was metastatic in 49.1% of cases (111/226 patients) and negative in 50.9% (115/226). The incidence of false-negative cases was 2.6% (2/115 patients). The predictive value of the sentinel lymph node was 98.7%. Finally, lymph-mode mapping is possible is a very high percentage of patients and therefore it is always advisable to use all three methods of identification together. The diagnostic reliability of sentinel lymph-node status is equally high. At present there no studies are available with a long-term follow-up to confirm these findings, and therefore axillary dissection is still the standard surgical treatment for breast cancer.

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