Using the Trace Element Contents in Bronchoalveolar Lavages to Probe the Human Exposure to Inhaled Particulates

Paolo Censi, Elisa Tamburo, Angela Cuttitta, Pierpaolo Zuddas, Paolo Censi, Thomas H. Darrah

Risultato della ricerca: Chapter

Abstract

Explosive volcanic eruptions eject large volumes of high surface area, metal-rich dust and ash into the atmosphere. In areas near major volcanic eruptions, humans often interact with these materials and may bioaccumulate heavy and toxic metals. To evaluate these interactions, we examine bronchoalveolar lavage samples (BAL) collected from people exposed to the paroxysmal 2001 Etna eruption. BAL samples reveal a strong enrichment of many toxic heavy metals and the capacity for trace elements released from inhaled particles to induce crystallisation of phosphatic microcryst biominerals in intraaveolar spaces. BAL rare earth element (REE) concentration patterns normalised to shale reveal a ‘V-shaped’ feature caused by the depletion of elements from Nd to Tb (mid-REEs) as compared to the variable enrichments of heavy lanthanides, Y, La and Ce. This pattern is consistent with solutions that experience phosphate mineral crystallisation in laboratory conditions and suggests that phosphate precipitation occurs in vivo in the lungs through interactions between volcanic particles and lung fluids. The BAL trace element patterns allow us to reconstruct the source of inhaled materials and depict the fluid mineral processes that occur between lung fluids and inhaled particles.
Lingua originaleEnglish
Titolo della pubblicazione ospiteMedical Geochemistry Geological Materials and Health
Pagine1-18
Numero di pagine18
Stato di pubblicazionePublished - 2013

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rare earth element
volcanic eruption
probe
trace element
fluid
crystallization
phosphate
heavy metal
mineral
explosive
shale
ash
surface area
dust
atmosphere
metal
exposure
particle
material
toxic metal

All Science Journal Classification (ASJC) codes

  • Earth and Planetary Sciences(all)

Cita questo

Censi, P., Tamburo, E., Cuttitta, A., Zuddas, P., Censi, P., & Darrah, T. H. (2013). Using the Trace Element Contents in Bronchoalveolar Lavages to Probe the Human Exposure to Inhaled Particulates. In Medical Geochemistry Geological Materials and Health (pagg. 1-18)

Using the Trace Element Contents in Bronchoalveolar Lavages to Probe the Human Exposure to Inhaled Particulates. / Censi, Paolo; Tamburo, Elisa; Cuttitta, Angela; Zuddas, Pierpaolo; Censi, Paolo; Darrah, Thomas H.

Medical Geochemistry Geological Materials and Health. 2013. pag. 1-18.

Risultato della ricerca: Chapter

Censi, P, Tamburo, E, Cuttitta, A, Zuddas, P, Censi, P & Darrah, TH 2013, Using the Trace Element Contents in Bronchoalveolar Lavages to Probe the Human Exposure to Inhaled Particulates. in Medical Geochemistry Geological Materials and Health. pagg. 1-18.
Censi P, Tamburo E, Cuttitta A, Zuddas P, Censi P, Darrah TH. Using the Trace Element Contents in Bronchoalveolar Lavages to Probe the Human Exposure to Inhaled Particulates. In Medical Geochemistry Geological Materials and Health. 2013. pag. 1-18
Censi, Paolo ; Tamburo, Elisa ; Cuttitta, Angela ; Zuddas, Pierpaolo ; Censi, Paolo ; Darrah, Thomas H. / Using the Trace Element Contents in Bronchoalveolar Lavages to Probe the Human Exposure to Inhaled Particulates. Medical Geochemistry Geological Materials and Health. 2013. pagg. 1-18
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