Using synchrotrons and XFELs for time-resolved X-ray crystallography and solution scattering experiments on biomolecules

Matteo Levantino, Briony A. Yorke, Diana C.F. Monteiro, Arwen R. Pearson, Marco Cammarata

Risultato della ricerca: Article

50 Citazioni (Scopus)

Abstract

Time-resolved structural information is key to understand the mechanism of biological processes, such as catalysis and signalling. Recent developments in X-ray sources as well as data collection and analysis methods are making routine time-resolved X-ray crystallography and solution scattering experiments a real possibility for structural biologists. Here we review the information that can be obtained from these techniques and discuss the considerations that must be taken into account when designing a time-resolved experiment.
Lingua originaleEnglish
pagine (da-a)41-48
Numero di pagine8
RivistaCurrent Opinion in Structural Biology
Volume35
Stato di pubblicazionePublished - 2015

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All Science Journal Classification (ASJC) codes

  • Structural Biology
  • Molecular Biology

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