Abstract

With the high occurrence of cardiovascular disease and increasing numbers of patients requiring vascular access, there is a significant need for smaller-diameter (>6 mm inner diameter) vascular graft that can provide long-term patency. Despite the technological improvements, restenosis and graft thrombosis continue to hamper the success of the implants. Vascular tissue engineering is a new field that has undergone enormous growth over the last decade and has proposed valid solutions for blood vessels repair. The goal of vascular tissue engineering is to produce neovessels and neoorgan tissue from autologous cells using a biodegradable polymer as a scaffold. The most important advantage of tissue-engineered implants is that these tissue can grow, remodel, rebuild, and respond to injury. This review describes the development of polymeric materials over the years and current tissue engineering strategies for the improvement of vascular conduits.
Lingua originaleEnglish
Numero di pagine0
RivistaInternational Journal of Polymer Science
Volume2014
Stato di pubblicazionePublished - 2014

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Scaffolds (biology)
Tissue engineering
Tissue
Grafts
Biodegradable polymers
Blood vessels
Scaffolds
Repair
Polymers

All Science Journal Classification (ASJC) codes

  • Polymers and Plastics

Cita questo

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title = "USING POLYMERIC SCAFFOLDS FOR VASCULAR TISSUE ENGINEERING",
abstract = "With the high occurrence of cardiovascular disease and increasing numbers of patients requiring vascular access, there is a significant need for smaller-diameter (>6 mm inner diameter) vascular graft that can provide long-term patency. Despite the technological improvements, restenosis and graft thrombosis continue to hamper the success of the implants. Vascular tissue engineering is a new field that has undergone enormous growth over the last decade and has proposed valid solutions for blood vessels repair. The goal of vascular tissue engineering is to produce neovessels and neoorgan tissue from autologous cells using a biodegradable polymer as a scaffold. The most important advantage of tissue-engineered implants is that these tissue can grow, remodel, rebuild, and respond to injury. This review describes the development of polymeric materials over the years and current tissue engineering strategies for the improvement of vascular conduits.",
author = "Calogero Fiorica and {Lo Monte}, {Attilio Ignazio} and Giuseppe Damiano and Alida Abruzzo and Palumbo, {Fabio Salvatore} and Roberta Altomare and Palumbo, {Vincenzo Davide} and Gioviale, {Maria Concetta} and Giovanni Tomasello and Gaetano Giammona and Mariano Licciardi",
year = "2014",
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TY - JOUR

T1 - USING POLYMERIC SCAFFOLDS FOR VASCULAR TISSUE ENGINEERING

AU - Fiorica, Calogero

AU - Lo Monte, Attilio Ignazio

AU - Damiano, Giuseppe

AU - Abruzzo, Alida

AU - Palumbo, Fabio Salvatore

AU - Altomare, Roberta

AU - Palumbo, Vincenzo Davide

AU - Gioviale, Maria Concetta

AU - Tomasello, Giovanni

AU - Giammona, Gaetano

AU - Licciardi, Mariano

PY - 2014

Y1 - 2014

N2 - With the high occurrence of cardiovascular disease and increasing numbers of patients requiring vascular access, there is a significant need for smaller-diameter (>6 mm inner diameter) vascular graft that can provide long-term patency. Despite the technological improvements, restenosis and graft thrombosis continue to hamper the success of the implants. Vascular tissue engineering is a new field that has undergone enormous growth over the last decade and has proposed valid solutions for blood vessels repair. The goal of vascular tissue engineering is to produce neovessels and neoorgan tissue from autologous cells using a biodegradable polymer as a scaffold. The most important advantage of tissue-engineered implants is that these tissue can grow, remodel, rebuild, and respond to injury. This review describes the development of polymeric materials over the years and current tissue engineering strategies for the improvement of vascular conduits.

AB - With the high occurrence of cardiovascular disease and increasing numbers of patients requiring vascular access, there is a significant need for smaller-diameter (>6 mm inner diameter) vascular graft that can provide long-term patency. Despite the technological improvements, restenosis and graft thrombosis continue to hamper the success of the implants. Vascular tissue engineering is a new field that has undergone enormous growth over the last decade and has proposed valid solutions for blood vessels repair. The goal of vascular tissue engineering is to produce neovessels and neoorgan tissue from autologous cells using a biodegradable polymer as a scaffold. The most important advantage of tissue-engineered implants is that these tissue can grow, remodel, rebuild, and respond to injury. This review describes the development of polymeric materials over the years and current tissue engineering strategies for the improvement of vascular conduits.

UR - http://hdl.handle.net/10447/95400

M3 - Article

VL - 2014

JO - International Journal of Polymer Science

JF - International Journal of Polymer Science

SN - 1687-9422

ER -