Triggering of Toll-like receptors in the elderly. A pilotstudy relevant for vaccination

Risultato della ricerca: Otherpeer review

Abstract

The impaired ability of the elderly to mount an efficient immune responseafter exposure to microbes or vaccines represents a major challengein protection against pathogens in ageing. Recently studies haveshown that stimulation of Toll-like receptors (TLRs), using stimulatoryligands, can enhance vaccine efficacy by a number of mechanisms,including the activation of innate immune cells and the consequentproduction of inflammatory cytokines.
Lingua originaleEnglish
Pagine79-90
Numero di pagine12
Stato di pubblicazionePublished - 2017

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