TREATMENT OF VISCERAL LEISHMANIASIS IN CHILDREN USING LIPOSOMAL AMPHOTHERICIN B

Antonio Cascio, Raimondi, Loredana Tasso, Massimo Pettoello- Mantovani, Marina Gramiccia, Scotti, Luigi Gradoni, Lucio Di Martino, Bryceson, Cascio, Raffaella Giacchino, Elio Castagnola, Robert N. Davidson

Risultato della ricerca: Articlepeer review

67 Citazioni (Scopus)

Abstract

We used liposomal amphotericin B as first-choice treatment of visceral leishmaniasis in 106 immunocompetent children who acquired the infection in a temperate region of southern Europe (Italy) where Leishmania infantum visceral leishmaniasis is endemic. The aim of the study was to identify the minimum total dose of liposomal amphotericin B needed to cure the infection in children and reduce the period of hospitalization. We conclude that the optimal regimen in immunocompetent children with L. infantum visceral leishmaniasis to be a total dose of 18 mg/kg of liposomal amphotericin B (3 mg/kg per day for 5 days, followed by 3 mg/kg administered as an outpatient regimen on day 10).
Lingua originaleEnglish
pagine (da-a)271-277
Numero di pagine7
RivistaJournal of Pediatrics
Volume131
Stato di pubblicazionePublished - 1997

All Science Journal Classification (ASJC) codes

  • Pediatrics, Perinatology, and Child Health

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