Abstract
PURPOSE:To evaluate the changes of the Oscillatory Potentials (OPs) of Electroretinogram (ERG) caused by short-term hypertension in human subjects, and their relationship with ocular perfusion pressure (OPP).METHODS:Suction cup technique in 12 normal volunteers with OPs simultaneously recording.RESULTS:Scotopic and photopic OPs were altered during OPP drop. Scotopic OPs showed more sensitiveness, with higher reduction (from 21% to 47%), when compared to the basal value, than in photopic recordings (from 14% to 34%). In both conditions, the relationship between OPP and OPs presented a steady amplitude before the trough after the +30 step, and rapid recovery after OPP normalisation. ANOVA and correlation analysis confirmed the data.CONCLUSION:The ERG OPs seemed to reflect the OPP modification. The features of OPs amplitudes suggest involvement of the retinal autoregulation mechanism and support development for further clinical studies.
Lingua originale | English |
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pagine (da-a) | 1341-1348 |
Rivista | Vision Research |
Volume | 45 |
Stato di pubblicazione | Published - 2005 |
All Science Journal Classification (ASJC) codes
- ???subjectarea.asjc.2700.2731???
- ???subjectarea.asjc.2800.2809???