Transformation of primary human hepatocytes in hepatocellular carcinoma.

Mauro Montalbano, Tiziana Corsello, Renza Vento, Tiziana Corsello, Mauro Montalbano, Mahmoud A. Eltorky, Cristiana Rastellini, Luca Cicalese, Renza Vento, Xiaofu Wang

Risultato della ricerca: Articlepeer review

5 Citazioni (Scopus)

Abstract

The present study investigated primary human hepatocyte cultures obtained from liver specimens of patients affected by cirrhosis and HCC, their proliferation and transformation. The degree of invasiveness of cells acquiring neoplastic characteristics was studied with a transwell migration assay. With the present study, we are the first to have identified and describe the existence of humanhepatocytes near the cancerous lesion that can transform in HCC in vitro.
Lingua originaleEnglish
pagine (da-a)1205-1217
Numero di pagine13
RivistaInternational Journal of Oncology
Volume48
Stato di pubblicazionePublished - 2015

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.1300.1306???

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