Transformation of primary human hepatocytes in hepatocellular carcinoma.

Mauro Montalbano; Tiziana Corsello; Renza Vento; Tiziana Corsello; Mauro Montalbano; Mahmoud A. Eltorky; Cristiana Rastellini; Luca Cicalese; Renza Vento; Xiaofu Wang

Transformation of primary human hepatocytes in hepatocellular carcinoma.

Mauro Montalbano, Tiziana Corsello, Renza Vento, Tiziana Corsello, Mauro Montalbano, Mahmoud A. Eltorky, Cristiana Rastellini, Luca Cicalese, Renza Vento, Xiaofu Wang

Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche

Risultato della ricerca: Article › peer review

6 Citazioni (Scopus)

Abstract

The present study investigated primary human hepatocyte cultures obtained from liver specimens of patients affected by cirrhosis and HCC, their proliferation and transformation. The degree of invasiveness of cells acquiring neoplastic characteristics was studied with a transwell migration assay. With the present study, we are the first to have identified and describe the existence of humanhepatocytes near the cancerous lesion that can transform in HCC in vitro.

Lingua originale	English
pagine (da-a)	1205-1217
Numero di pagine	13
Rivista	International Journal of Oncology
Volume	48
Stato di pubblicazione	Published - 2015

All Science Journal Classification (ASJC) codes

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???subjectarea.asjc.1300.1306???

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@article{161a881bc6104929bba0bf08ff1ea79f,

title = "Transformation of primary human hepatocytes in hepatocellular carcinoma.",

abstract = "The present study investigated primary human hepatocyte cultures obtained from liver specimens of patients affected by cirrhosis and HCC, their proliferation and transformation. The degree of invasiveness of cells acquiring neoplastic characteristics was studied with a transwell migration assay. With the present study, we are the first to have identified and describe the existence of humanhepatocytes near the cancerous lesion that can transform in HCC in vitro.",

author = "Mauro Montalbano and Tiziana Corsello and Renza Vento and Tiziana Corsello and Mauro Montalbano and Eltorky, {Mahmoud A.} and Cristiana Rastellini and Luca Cicalese and Renza Vento and Xiaofu Wang",

year = "2015",

language = "English",

volume = "48",

pages = "1205--1217",

journal = "International Journal of Oncology",

issn = "1019-6439",

publisher = "Spandidos Publications",

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TY - JOUR

T1 - Transformation of primary human hepatocytes in hepatocellular carcinoma.

AU - Montalbano, Mauro

AU - Corsello, Tiziana

AU - Vento, Renza

AU - Corsello, Tiziana

AU - Montalbano, Mauro

AU - Eltorky, Mahmoud A.

AU - Rastellini, Cristiana

AU - Cicalese, Luca

AU - Vento, Renza

AU - Wang, Xiaofu

PY - 2015

Y1 - 2015

N2 - The present study investigated primary human hepatocyte cultures obtained from liver specimens of patients affected by cirrhosis and HCC, their proliferation and transformation. The degree of invasiveness of cells acquiring neoplastic characteristics was studied with a transwell migration assay. With the present study, we are the first to have identified and describe the existence of humanhepatocytes near the cancerous lesion that can transform in HCC in vitro.

AB - The present study investigated primary human hepatocyte cultures obtained from liver specimens of patients affected by cirrhosis and HCC, their proliferation and transformation. The degree of invasiveness of cells acquiring neoplastic characteristics was studied with a transwell migration assay. With the present study, we are the first to have identified and describe the existence of humanhepatocytes near the cancerous lesion that can transform in HCC in vitro.

UR - http://hdl.handle.net/10447/163853

M3 - Article

SN - 1019-6439

VL - 48

SP - 1205

EP - 1217

JO - International Journal of Oncology

JF - International Journal of Oncology

ER -

Transformation of primary human hepatocytes in hepatocellular carcinoma.

Abstract

All Science Journal Classification (ASJC) codes

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