Towards bioarrays of cellular-like compartments for monitoring few molecular binding events

Bruno Giuseppe Pignataro; Maurizio Leone; Valeria Vetri; Giuseppe Domenico Arrabito; Felicia Cavaleri; Vincenza Montalbano

Towards bioarrays of cellular-like compartments for monitoring few molecular binding events

Bruno Giuseppe Pignataro, Maurizio Leone, Valeria Vetri, Giuseppe Domenico Arrabito, Felicia Cavaleri, Vincenza Montalbano

Risultato della ricerca: Other › peer review

Abstract

The aim of this work is to artificially reproduce scalable cellular-like compartments on a chip, thus realizing specialized small volume systems to study the behaviour of interacting biomolecules by few binding events. In particular, we show an unprecedented solution-based protein-binding assay based on arrays of oil-confined water droplets containing protein targets, labelled ligands and other compounds.

Lingua originale	English
Numero di pagine	1
Stato di pubblicazione	Published - 2016

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title = "Towards bioarrays of cellular-like compartments for monitoring few molecular binding events",

abstract = "The aim of this work is to artificially reproduce scalable cellular-like compartments on a chip, thus realizing specialized small volume systems to study the behaviour of interacting biomolecules by few binding events. In particular, we show an unprecedented solution-based protein-binding assay based on arrays of oil-confined water droplets containing protein targets, labelled ligands and other compounds.",

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TY - CONF

T1 - Towards bioarrays of cellular-like compartments for monitoring few molecular binding events

AU - Pignataro, Bruno Giuseppe

AU - Leone, Maurizio

AU - Vetri, Valeria

AU - Arrabito, Giuseppe Domenico

AU - Cavaleri, Felicia

AU - Montalbano, Vincenza

PY - 2016

Y1 - 2016

N2 - The aim of this work is to artificially reproduce scalable cellular-like compartments on a chip, thus realizing specialized small volume systems to study the behaviour of interacting biomolecules by few binding events. In particular, we show an unprecedented solution-based protein-binding assay based on arrays of oil-confined water droplets containing protein targets, labelled ligands and other compounds.

AB - The aim of this work is to artificially reproduce scalable cellular-like compartments on a chip, thus realizing specialized small volume systems to study the behaviour of interacting biomolecules by few binding events. In particular, we show an unprecedented solution-based protein-binding assay based on arrays of oil-confined water droplets containing protein targets, labelled ligands and other compounds.

KW - Raster Image Correlation Spectroscopy

KW - Water-in-oil droplets

KW - inkjet printing

KW - Raster Image Correlation Spectroscopy

KW - Water-in-oil droplets

KW - inkjet printing

UR - http://hdl.handle.net/10447/227891

M3 - Other

ER -