Three-year results of repaired barlow mitral valves via right minithoracotomy versus median sternotomy in a randomized trial

Khalil Fattouch, Giuseppe Nasso, Khalil Fattouch, Giuseppe Speziale, Giuseppe Rosano, Francesco Bartolomucci, Raffaele Bonifazi, Mauro Del Giglio, Vito Romano, Graziano Riccioni, Giuseppe Del Prete, Francesco Massari

Risultato della ricerca: Article

8 Citazioni (Scopus)

Abstract

Objectives: To clarify whether the results of repair of a complex mitral lesion (Barlow valve) at the intermediate-term follow-up are independent of the mode of surgical access [minithoracotomy vs. median sternotomy (MS)]. Methods: In a prospective randomized study of mitral repair for Barlow disease using either a minimally invasive (MI) approach or MS, we achieved an average follow-up of 3 years (echocardiography, physical examination and quality of life). Mitral repair was achieved with polytetrafluoroethylene chordal implantation for both leaflets. Results: Both groups included 80 patients. Mechanical ventilation time and intensive care unit and hospital stay were shorter in the MI group (p = 0.01, p = 0.013 and p = 0.02, respectively). During the follow-up, 5 patients in each group (6.25%) displayed mild mitral regurgitation, while 2 patients in each group (2.5%) developed recurrent regurgitation graded as at least moderate/severe. The rate of mitral reoperation was 2.5% in the MI group and 1.25% in the MS group (p = 0.9). The overall follow-up mortality was 3.75% in both the MI and the MS groups. Conclusions: The 3-year results of repair of Barlow valves were satisfactory irrespective of the approach used to repair the valve. The advantages of MI surgery can be achieved in patients with mitral Barlow disease without concerns over the durability of repair. © 2014 S. Karger AG, Basel.
Lingua originaleEnglish
pagine (da-a)97-105
Numero di pagine9
RivistaCardiology
Volume128
Stato di pubblicazionePublished - 2014

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Sternotomy
Mitral Valve
Minimally Invasive Surgical Procedures
Polytetrafluoroethylene
Mitral Valve Insufficiency
Reoperation
Artificial Respiration
Physical Examination
Intensive Care Units
Echocardiography
Length of Stay
Quality of Life
Prospective Studies
Mortality

All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)

Cita questo

Fattouch, K., Nasso, G., Fattouch, K., Speziale, G., Rosano, G., Bartolomucci, F., ... Massari, F. (2014). Three-year results of repaired barlow mitral valves via right minithoracotomy versus median sternotomy in a randomized trial. Cardiology, 128, 97-105.

Three-year results of repaired barlow mitral valves via right minithoracotomy versus median sternotomy in a randomized trial. / Fattouch, Khalil; Nasso, Giuseppe; Fattouch, Khalil; Speziale, Giuseppe; Rosano, Giuseppe; Bartolomucci, Francesco; Bonifazi, Raffaele; Del Giglio, Mauro; Romano, Vito; Riccioni, Graziano; Del Prete, Giuseppe; Massari, Francesco.

In: Cardiology, Vol. 128, 2014, pag. 97-105.

Risultato della ricerca: Article

Fattouch, K, Nasso, G, Fattouch, K, Speziale, G, Rosano, G, Bartolomucci, F, Bonifazi, R, Del Giglio, M, Romano, V, Riccioni, G, Del Prete, G & Massari, F 2014, 'Three-year results of repaired barlow mitral valves via right minithoracotomy versus median sternotomy in a randomized trial', Cardiology, vol. 128, pagg. 97-105.
Fattouch, Khalil ; Nasso, Giuseppe ; Fattouch, Khalil ; Speziale, Giuseppe ; Rosano, Giuseppe ; Bartolomucci, Francesco ; Bonifazi, Raffaele ; Del Giglio, Mauro ; Romano, Vito ; Riccioni, Graziano ; Del Prete, Giuseppe ; Massari, Francesco. / Three-year results of repaired barlow mitral valves via right minithoracotomy versus median sternotomy in a randomized trial. In: Cardiology. 2014 ; Vol. 128. pagg. 97-105.
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title = "Three-year results of repaired barlow mitral valves via right minithoracotomy versus median sternotomy in a randomized trial",
abstract = "Objectives: To clarify whether the results of repair of a complex mitral lesion (Barlow valve) at the intermediate-term follow-up are independent of the mode of surgical access [minithoracotomy vs. median sternotomy (MS)]. Methods: In a prospective randomized study of mitral repair for Barlow disease using either a minimally invasive (MI) approach or MS, we achieved an average follow-up of 3 years (echocardiography, physical examination and quality of life). Mitral repair was achieved with polytetrafluoroethylene chordal implantation for both leaflets. Results: Both groups included 80 patients. Mechanical ventilation time and intensive care unit and hospital stay were shorter in the MI group (p = 0.01, p = 0.013 and p = 0.02, respectively). During the follow-up, 5 patients in each group (6.25{\%}) displayed mild mitral regurgitation, while 2 patients in each group (2.5{\%}) developed recurrent regurgitation graded as at least moderate/severe. The rate of mitral reoperation was 2.5{\%} in the MI group and 1.25{\%} in the MS group (p = 0.9). The overall follow-up mortality was 3.75{\%} in both the MI and the MS groups. Conclusions: The 3-year results of repair of Barlow valves were satisfactory irrespective of the approach used to repair the valve. The advantages of MI surgery can be achieved in patients with mitral Barlow disease without concerns over the durability of repair. {\circledC} 2014 S. Karger AG, Basel.",
keywords = "Follow-up; Minimally invasive surgery; Mitral valve repair; Female; Follow-Up Studies; Genetic Diseases, X-Linked; Humans; Male; Middle Aged; Mitral Valve; Mitral Valve Insufficiency; Mitral Valve Prolapse; Mitral Valve Stenosis; Prospective Studies; Quality of Life; Sternotomy; Thoracotomy; Treatment Outcome; Cardiology and Cardiovascular Medicine; Pharmacology (medical); Medicine (all)",
author = "Khalil Fattouch and Giuseppe Nasso and Khalil Fattouch and Giuseppe Speziale and Giuseppe Rosano and Francesco Bartolomucci and Raffaele Bonifazi and {Del Giglio}, Mauro and Vito Romano and Graziano Riccioni and {Del Prete}, Giuseppe and Francesco Massari",
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T1 - Three-year results of repaired barlow mitral valves via right minithoracotomy versus median sternotomy in a randomized trial

AU - Fattouch, Khalil

AU - Nasso, Giuseppe

AU - Fattouch, Khalil

AU - Speziale, Giuseppe

AU - Rosano, Giuseppe

AU - Bartolomucci, Francesco

AU - Bonifazi, Raffaele

AU - Del Giglio, Mauro

AU - Romano, Vito

AU - Riccioni, Graziano

AU - Del Prete, Giuseppe

AU - Massari, Francesco

PY - 2014

Y1 - 2014

N2 - Objectives: To clarify whether the results of repair of a complex mitral lesion (Barlow valve) at the intermediate-term follow-up are independent of the mode of surgical access [minithoracotomy vs. median sternotomy (MS)]. Methods: In a prospective randomized study of mitral repair for Barlow disease using either a minimally invasive (MI) approach or MS, we achieved an average follow-up of 3 years (echocardiography, physical examination and quality of life). Mitral repair was achieved with polytetrafluoroethylene chordal implantation for both leaflets. Results: Both groups included 80 patients. Mechanical ventilation time and intensive care unit and hospital stay were shorter in the MI group (p = 0.01, p = 0.013 and p = 0.02, respectively). During the follow-up, 5 patients in each group (6.25%) displayed mild mitral regurgitation, while 2 patients in each group (2.5%) developed recurrent regurgitation graded as at least moderate/severe. The rate of mitral reoperation was 2.5% in the MI group and 1.25% in the MS group (p = 0.9). The overall follow-up mortality was 3.75% in both the MI and the MS groups. Conclusions: The 3-year results of repair of Barlow valves were satisfactory irrespective of the approach used to repair the valve. The advantages of MI surgery can be achieved in patients with mitral Barlow disease without concerns over the durability of repair. © 2014 S. Karger AG, Basel.

AB - Objectives: To clarify whether the results of repair of a complex mitral lesion (Barlow valve) at the intermediate-term follow-up are independent of the mode of surgical access [minithoracotomy vs. median sternotomy (MS)]. Methods: In a prospective randomized study of mitral repair for Barlow disease using either a minimally invasive (MI) approach or MS, we achieved an average follow-up of 3 years (echocardiography, physical examination and quality of life). Mitral repair was achieved with polytetrafluoroethylene chordal implantation for both leaflets. Results: Both groups included 80 patients. Mechanical ventilation time and intensive care unit and hospital stay were shorter in the MI group (p = 0.01, p = 0.013 and p = 0.02, respectively). During the follow-up, 5 patients in each group (6.25%) displayed mild mitral regurgitation, while 2 patients in each group (2.5%) developed recurrent regurgitation graded as at least moderate/severe. The rate of mitral reoperation was 2.5% in the MI group and 1.25% in the MS group (p = 0.9). The overall follow-up mortality was 3.75% in both the MI and the MS groups. Conclusions: The 3-year results of repair of Barlow valves were satisfactory irrespective of the approach used to repair the valve. The advantages of MI surgery can be achieved in patients with mitral Barlow disease without concerns over the durability of repair. © 2014 S. Karger AG, Basel.

KW - Follow-up; Minimally invasive surgery; Mitral valve repair; Female; Follow-Up Studies; Genetic Diseases, X-Linked; Humans; Male; Middle Aged; Mitral Valve; Mitral Valve Insufficiency; Mitral Valve Prolapse; Mitral Valve Stenosis; Prospective Studies; Qual

UR - http://hdl.handle.net/10447/212048

UR - http://www.karger.ch/journals/crd/crd_jh.htm

M3 - Article

VL - 128

SP - 97

EP - 105

JO - Cardiology

JF - Cardiology

SN - 0008-6312

ER -