Three-year results of repaired barlow mitral valves via right minithoracotomy versus median sternotomy in a randomized trial

Khalil Fattouch, Raffaele Bonifazi, Mauro Del Giglio, Vito Romano, Graziano Riccioni, Giuseppe Del Prete, Francesco Massari, Giuseppe Nasso, Khalil Fattouch, Giuseppe Speziale, Giuseppe Rosano, Francesco Bartolomucci

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Abstract

Objectives: To clarify whether the results of repair of a complex mitral lesion (Barlow valve) at the intermediate-term follow-up are independent of the mode of surgical access [minithoracotomy vs. median sternotomy (MS)]. Methods: In a prospective randomized study of mitral repair for Barlow disease using either a minimally invasive (MI) approach or MS, we achieved an average follow-up of 3 years (echocardiography, physical examination and quality of life). Mitral repair was achieved with polytetrafluoroethylene chordal implantation for both leaflets. Results: Both groups included 80 patients. Mechanical ventilation time and intensive care unit and hospital stay were shorter in the MI group (p = 0.01, p = 0.013 and p = 0.02, respectively). During the follow-up, 5 patients in each group (6.25%) displayed mild mitral regurgitation, while 2 patients in each group (2.5%) developed recurrent regurgitation graded as at least moderate/severe. The rate of mitral reoperation was 2.5% in the MI group and 1.25% in the MS group (p = 0.9). The overall follow-up mortality was 3.75% in both the MI and the MS groups. Conclusions: The 3-year results of repair of Barlow valves were satisfactory irrespective of the approach used to repair the valve. The advantages of MI surgery can be achieved in patients with mitral Barlow disease without concerns over the durability of repair. © 2014 S. Karger AG, Basel.
Lingua originaleEnglish
pagine (da-a)97-105
Numero di pagine9
RivistaCardiology
Volume128
Stato di pubblicazionePublished - 2014

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All Science Journal Classification (ASJC) codes

  • Cardiology and Cardiovascular Medicine
  • Pharmacology (medical)

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Fattouch, K., Bonifazi, R., Del Giglio, M., Romano, V., Riccioni, G., Del Prete, G., Massari, F., Nasso, G., Fattouch, K., Speziale, G., Rosano, G., & Bartolomucci, F. (2014). Three-year results of repaired barlow mitral valves via right minithoracotomy versus median sternotomy in a randomized trial. Cardiology, 128, 97-105.