The Reactivity of 4’-Substituted Spiro[Isoindole-1,3’-pyrazoles] Derivatives: Substitution/Elimination Reactions and Access to Biaryl Derivatives

Giuseppe Daidone; Demetrio Raffa; Angela Maria Ingarra; Gianfranco Fontana; Benedetta Maggio; Fabiana Plescia; Maria Valeria Raimondi

The Reactivity of 4’-Substituted Spiro[Isoindole-1,3’-pyrazoles] Derivatives: Substitution/Elimination Reactions and Access to Biaryl Derivatives

Giuseppe Daidone, Demetrio Raffa, Angela Maria Ingarra, Gianfranco Fontana, Benedetta Maggio, Fabiana Plescia, Maria Valeria Raimondi

Scienze e Tecnologie Biologiche Chimiche e Farmaceutiche

Risultato della ricerca: Article › peer review

Abstract

This paper describes aspects of the chemistry of 4’-substituted spiro [indole-1,3’-pyrazoles]. These compounds underwent substitution and/or elimination reactions to afford some new spiro- as well as biaryl derivatives of potential pharmaceutical relevance. Mechanistic considerations are discussed as well.

Lingua originale	English
pagine (da-a)	241-254
Numero di pagine	14
Rivista	Heterocycles
Volume	94
Stato di pubblicazione	Published - 2017

All Science Journal Classification (ASJC) codes

Analytical Chemistry
Pharmacology
Organic Chemistry

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The Reactivity of 4’-Substituted Spiro[Isoindole-1,3’-pyrazoles] Derivatives: Substitution/Elimination Reactions and Access to Biaryl Derivatives. / Daidone, Giuseppe ; Raffa, Demetrio ; Ingarra, Angela Maria ; Fontana, Gianfranco ; Maggio, Benedetta ; Plescia, Fabiana ; Raimondi, Maria Valeria.

In: Heterocycles, Vol. 94, 2017, pag. 241-254.

Risultato della ricerca: Article › peer review

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AB - This paper describes aspects of the chemistry of 4’-substituted spiro [indole-1,3’-pyrazoles]. These compounds underwent substitution and/or elimination reactions to afford some new spiro- as well as biaryl derivatives of potential pharmaceutical relevance. Mechanistic considerations are discussed as well.

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