The Reactivity of 4’-Substituted Spiro[Isoindole-1,3’-pyrazoles] Derivatives: Substitution/Elimination Reactions and Access to Biaryl Derivatives

Demetrio Raffa, Benedetta Maggio, Maria Valeria Raimondi, Gianfranco Fontana, Angela Maria Ingarra, Fabiana Plescia, Giuseppe Daidone

Risultato della ricerca: Article

Abstract

This paper describes aspects of the chemistry of 4’-substituted spiro [indole-1,3’-pyrazoles]. These compounds underwent substitution and/or elimination reactions to afford some new spiro- as well as biaryl derivatives of potential pharmaceutical relevance. Mechanistic considerations are discussed as well.
Lingua originaleEnglish
pagine (da-a)241-254
Numero di pagine14
RivistaDefault journal
Volume94
Stato di pubblicazionePublished - 2017

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Isoindoles
Pyrazoles
Substitution reactions
Derivatives
Pharmaceutical Preparations
indole

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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The Reactivity of 4’-Substituted Spiro[Isoindole-1,3’-pyrazoles] Derivatives: Substitution/Elimination Reactions and Access to Biaryl Derivatives. / Raffa, Demetrio; Maggio, Benedetta; Raimondi, Maria Valeria; Fontana, Gianfranco; Ingarra, Angela Maria; Plescia, Fabiana; Daidone, Giuseppe.

In: Default journal, Vol. 94, 2017, pag. 241-254.

Risultato della ricerca: Article

Raffa, D, Maggio, B, Raimondi, MV, Fontana, G, Ingarra, AM, Plescia, F & Daidone, G 2017, 'The Reactivity of 4’-Substituted Spiro[Isoindole-1,3’-pyrazoles] Derivatives: Substitution/Elimination Reactions and Access to Biaryl Derivatives', Default journal, vol. 94, pagg. 241-254.
Raffa D, Maggio B, Raimondi MV, Fontana G, Ingarra AM, Plescia F e altri. The Reactivity of 4’-Substituted Spiro[Isoindole-1,3’-pyrazoles] Derivatives: Substitution/Elimination Reactions and Access to Biaryl Derivatives. Default journal. 2017;94:241-254.
Raffa, Demetrio ; Maggio, Benedetta ; Raimondi, Maria Valeria ; Fontana, Gianfranco ; Ingarra, Angela Maria ; Plescia, Fabiana ; Daidone, Giuseppe. / The Reactivity of 4’-Substituted Spiro[Isoindole-1,3’-pyrazoles] Derivatives: Substitution/Elimination Reactions and Access to Biaryl Derivatives. In: Default journal. 2017 ; Vol. 94. pagg. 241-254.
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AU - Ingarra, Angela Maria

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