The Reactivity of 4’-Substituted Spiro[Isoindole-1,3’-pyrazoles] Derivatives: Substitution/Elimination Reactions and Access to Biaryl Derivatives

Risultato della ricerca: Article

Abstract

This paper describes aspects of the chemistry of 4’-substituted spiro [indole-1,3’-pyrazoles]. These compounds underwent substitution and/or elimination reactions to afford some new spiro- as well as biaryl derivatives of potential pharmaceutical relevance. Mechanistic considerations are discussed as well.
Lingua originaleEnglish
pagine (da-a)241-254
Numero di pagine14
RivistaDefault journal
Volume94
Stato di pubblicazionePublished - 2017

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Isoindoles
Pyrazoles
Substitution reactions
Derivatives
Pharmaceutical Preparations
indole

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Pharmacology
  • Organic Chemistry

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title = "The Reactivity of 4’-Substituted Spiro[Isoindole-1,3’-pyrazoles] Derivatives: Substitution/Elimination Reactions and Access to Biaryl Derivatives",
abstract = "This paper describes aspects of the chemistry of 4’-substituted spiro [indole-1,3’-pyrazoles]. These compounds underwent substitution and/or elimination reactions to afford some new spiro- as well as biaryl derivatives of potential pharmaceutical relevance. Mechanistic considerations are discussed as well.",
author = "Demetrio Raffa and Benedetta Maggio and Raimondi, {Maria Valeria} and Gianfranco Fontana and Ingarra, {Angela Maria} and Fabiana Plescia and Giuseppe Daidone",
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AU - Raffa, Demetrio

AU - Maggio, Benedetta

AU - Raimondi, Maria Valeria

AU - Fontana, Gianfranco

AU - Ingarra, Angela Maria

AU - Plescia, Fabiana

AU - Daidone, Giuseppe

PY - 2017

Y1 - 2017

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AB - This paper describes aspects of the chemistry of 4’-substituted spiro [indole-1,3’-pyrazoles]. These compounds underwent substitution and/or elimination reactions to afford some new spiro- as well as biaryl derivatives of potential pharmaceutical relevance. Mechanistic considerations are discussed as well.

UR - http://hdl.handle.net/10447/225112

M3 - Article

VL - 94

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