TY - JOUR
T1 - The prevalence of abnormal glucose regulation in patients with coronary artery disease across Europe: The Euro Heart Survey on diabetes and the heart
AU - Novo, Salvatore
AU - Coppola, Giuseppe
AU - Di Bernardi, Dario
AU - Zanetti, Marcella
AU - Martinez, Vito Bruno
PY - 2004
Y1 - 2004
N2 - Aim The objective behind the Euro Heart Survey on diabetes and the heart was to study the prevalence of abnormal glucose regulation in adult patients with coronary artery disease (CAD). Methods and results The survey engaged 110 centres in 25 countries recruiting 4196 patients referred to a cardiologist due to CAD out of whom 2107 were admitted on an acute basis and 2854 had an elective consultation. Patient data were collected via a web-based case record form. An oral glucose tolerance test (OGTT) was used for the characterisation of the glucose metabolism. Thirty-one per cent of the patients had diabetes. An OGTT was performed on the 1920 patients without known diabetes, of whom 923 had acute and 997 had a stable manifestation of CAD, respectively. In patients with acute CAD, 36% had impaired glucose regulation and 22% newly detected diabetes. In the stable group these proportions were 37% and 14%. Conclusion This survey demonstrates that normal glucose regulation is less common than abnormal glucose regulation in patients with CAD. OGTT easily discloses the glucometabolic state and should be a routine procedure. The knowledge of glucometabolic state among these patients should influence their future management because it has great potential to improve the outcome.
AB - Aim The objective behind the Euro Heart Survey on diabetes and the heart was to study the prevalence of abnormal glucose regulation in adult patients with coronary artery disease (CAD). Methods and results The survey engaged 110 centres in 25 countries recruiting 4196 patients referred to a cardiologist due to CAD out of whom 2107 were admitted on an acute basis and 2854 had an elective consultation. Patient data were collected via a web-based case record form. An oral glucose tolerance test (OGTT) was used for the characterisation of the glucose metabolism. Thirty-one per cent of the patients had diabetes. An OGTT was performed on the 1920 patients without known diabetes, of whom 923 had acute and 997 had a stable manifestation of CAD, respectively. In patients with acute CAD, 36% had impaired glucose regulation and 22% newly detected diabetes. In the stable group these proportions were 37% and 14%. Conclusion This survey demonstrates that normal glucose regulation is less common than abnormal glucose regulation in patients with CAD. OGTT easily discloses the glucometabolic state and should be a routine procedure. The knowledge of glucometabolic state among these patients should influence their future management because it has great potential to improve the outcome.
KW - Coronary artery disease; Diabetes mellitus; Impaired glucose tolerance; Oral glucose tolerance test; Adult; Aged; Blood Glucose; Coronary Artery Disease; Diabetes Mellitus
KW - Type 2; Diabetic Angiopathies; Europe; Female; Glucose Tolerance Test; Humans; Male; Middle Aged; Risk Factors
KW - Coronary artery disease; Diabetes mellitus; Impaired glucose tolerance; Oral glucose tolerance test; Adult; Aged; Blood Glucose; Coronary Artery Disease; Diabetes Mellitus
KW - Type 2; Diabetic Angiopathies; Europe; Female; Glucose Tolerance Test; Humans; Male; Middle Aged; Risk Factors
UR - http://hdl.handle.net/10447/365124
UR - http://eurheartj.oxfordjournals.org/
M3 - Article
SN - 0195-668X
VL - 25
SP - 1880
EP - 1890
JO - European Heart Journal
JF - European Heart Journal
ER -