The Nonvolatile and Volatile Metabolites of Prangos ferulacea and Their Biological Properties

Maurizio Bruno, Vincenzo Ilardi, Alessandro Venditti, Alessandro Venditti, Filippo Maggi, Luana Quassinti, Dennis Fiorini, Massimo Bramucci

Risultato della ricerca: Articlepeer review

1 Citazioni (Scopus)

Abstract

Prangos ferulacea (L.) Lindl. (Fam. Apiaceae), an orophilous species of eastern Mediterranean and western Asia, possesses a number of biological properties that are worthy of exploitation in different fields. Phytochemical investigations revealed the presence of coumarins, prenyl-coumarins, and furano-coumarins as the main constituents of this species, as well as several flavonoids. Among prenyl-coumarins, osthol is a promising apoptotic agent quite selective toward cancer cells. In addition, the essential oils have been extensively investigated, and several chemotypes have been identified. This work reviews the literature on this species published between 1965 and 2018, describes its volatile and nonvolatile metabolites, and outlines its pharmacological effects.
Lingua originaleEnglish
pagine (da-a)815-824
Numero di pagine10
RivistaPlanta Medica
Volume85
Stato di pubblicazionePublished - 2019

All Science Journal Classification (ASJC) codes

  • Analytical Chemistry
  • Molecular Medicine
  • Pharmacology
  • Pharmaceutical Science
  • Drug Discovery
  • Complementary and alternative medicine
  • Organic Chemistry

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