The management of multiple sclerosis by reference centers in Italy: health demands and needs in Campania region.

Walter Mazzucco, Walter Di Iorio, Roberta Lanzillo, Pasquale Vivo, Daniele Spitaleri, Leonardo Sinisi, Giuseppe Orefice, Felice Romano, Chiara De Waure, Walter Ricciardi, Maria Petracca, Giorgia Teresa Maniscalco, Francesco Di Nardo, Vincenzo Busillo, Mario Alberto Battaglia, Antonio Gallo, Darko Nedovic, Emilio Lombardi, Anna Pia Spadera

Risultato della ricerca: Article

4 Citazioni (Scopus)

Abstract

This cross-sectional study has investigated the diagnostic and therapeutic management of patients suffering from multiple sclerosis (MS) in the Campania Region (Italy). A survey involving all the reference centers for MS in Campania Region was conducted from March to August 2011. Centers responded to a web-administered questionnaire on management and clinical characteristics of MS patients. In the study period, 3263 patients (mean age 37 years, 66 % females) accessed the centers. Patients received a first diagnosis of MS in 161 cases (4.9 %). About 37 % of the subjects without a previous diagnosis came to the centers on their own initiative. All patients underwent a complete neurological examination and expanded disability status scale. The other most common investigations were magnetic resonance imaging (44.0 %) and evoked potentials (22.1 %). The number of treated patients was 2797 (87.1 %). The most used drugs were interferon b and glatiramer acetate. The time between diagnosis and initiation of therapy exceeded 6 months in 32 % of cases. Second-line drugs were under-used: 16 % of patients who might benefit from them show high clinical and radiological disease activity despite treatment with immunomodulant drugs. The MS care management of the surveyed centers showed consistent margins for improvement in 2011. Even though these data do not represent the current situation, they can be used to monitor improvements in MS care.
Lingua originaleEnglish
pagine (da-a)-
Numero di pagine8
RivistaNeurological Sciences
Stato di pubblicazionePublished - 2015

Fingerprint

Italy
Multiple Sclerosis
Health
Neurologic Examination
Evoked Potentials
Pharmaceutical Preparations
Interferons
Acetates
Therapeutics
Cross-Sectional Studies

All Science Journal Classification (ASJC) codes

  • Dermatology
  • Psychiatry and Mental health
  • Clinical Neurology

Cita questo

Mazzucco, W., Di Iorio, W., Lanzillo, R., Vivo, P., Spitaleri, D., Sinisi, L., ... Spadera, A. P. (2015). The management of multiple sclerosis by reference centers in Italy: health demands and needs in Campania region. Neurological Sciences, -.

The management of multiple sclerosis by reference centers in Italy: health demands and needs in Campania region. / Mazzucco, Walter; Di Iorio, Walter; Lanzillo, Roberta; Vivo, Pasquale; Spitaleri, Daniele; Sinisi, Leonardo; Orefice, Giuseppe; Romano, Felice; De Waure, Chiara; Ricciardi, Walter; Petracca, Maria; Maniscalco, Giorgia Teresa; Di Nardo, Francesco; Busillo, Vincenzo; Battaglia, Mario Alberto; Gallo, Antonio; Nedovic, Darko; Lombardi, Emilio; Spadera, Anna Pia.

In: Neurological Sciences, 2015, pag. -.

Risultato della ricerca: Article

Mazzucco, W, Di Iorio, W, Lanzillo, R, Vivo, P, Spitaleri, D, Sinisi, L, Orefice, G, Romano, F, De Waure, C, Ricciardi, W, Petracca, M, Maniscalco, GT, Di Nardo, F, Busillo, V, Battaglia, MA, Gallo, A, Nedovic, D, Lombardi, E & Spadera, AP 2015, 'The management of multiple sclerosis by reference centers in Italy: health demands and needs in Campania region.', Neurological Sciences, pagg. -.
Mazzucco, Walter ; Di Iorio, Walter ; Lanzillo, Roberta ; Vivo, Pasquale ; Spitaleri, Daniele ; Sinisi, Leonardo ; Orefice, Giuseppe ; Romano, Felice ; De Waure, Chiara ; Ricciardi, Walter ; Petracca, Maria ; Maniscalco, Giorgia Teresa ; Di Nardo, Francesco ; Busillo, Vincenzo ; Battaglia, Mario Alberto ; Gallo, Antonio ; Nedovic, Darko ; Lombardi, Emilio ; Spadera, Anna Pia. / The management of multiple sclerosis by reference centers in Italy: health demands and needs in Campania region. In: Neurological Sciences. 2015 ; pagg. -.
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title = "The management of multiple sclerosis by reference centers in Italy: health demands and needs in Campania region.",
abstract = "This cross-sectional study has investigated the diagnostic and therapeutic management of patients suffering from multiple sclerosis (MS) in the Campania Region (Italy). A survey involving all the reference centers for MS in Campania Region was conducted from March to August 2011. Centers responded to a web-administered questionnaire on management and clinical characteristics of MS patients. In the study period, 3263 patients (mean age 37 years, 66 {\%} females) accessed the centers. Patients received a first diagnosis of MS in 161 cases (4.9 {\%}). About 37 {\%} of the subjects without a previous diagnosis came to the centers on their own initiative. All patients underwent a complete neurological examination and expanded disability status scale. The other most common investigations were magnetic resonance imaging (44.0 {\%}) and evoked potentials (22.1 {\%}). The number of treated patients was 2797 (87.1 {\%}). The most used drugs were interferon b and glatiramer acetate. The time between diagnosis and initiation of therapy exceeded 6 months in 32 {\%} of cases. Second-line drugs were under-used: 16 {\%} of patients who might benefit from them show high clinical and radiological disease activity despite treatment with immunomodulant drugs. The MS care management of the surveyed centers showed consistent margins for improvement in 2011. Even though these data do not represent the current situation, they can be used to monitor improvements in MS care.",
author = "Walter Mazzucco and {Di Iorio}, Walter and Roberta Lanzillo and Pasquale Vivo and Daniele Spitaleri and Leonardo Sinisi and Giuseppe Orefice and Felice Romano and {De Waure}, Chiara and Walter Ricciardi and Maria Petracca and Maniscalco, {Giorgia Teresa} and {Di Nardo}, Francesco and Vincenzo Busillo and Battaglia, {Mario Alberto} and Antonio Gallo and Darko Nedovic and Emilio Lombardi and Spadera, {Anna Pia}",
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T1 - The management of multiple sclerosis by reference centers in Italy: health demands and needs in Campania region.

AU - Mazzucco, Walter

AU - Di Iorio, Walter

AU - Lanzillo, Roberta

AU - Vivo, Pasquale

AU - Spitaleri, Daniele

AU - Sinisi, Leonardo

AU - Orefice, Giuseppe

AU - Romano, Felice

AU - De Waure, Chiara

AU - Ricciardi, Walter

AU - Petracca, Maria

AU - Maniscalco, Giorgia Teresa

AU - Di Nardo, Francesco

AU - Busillo, Vincenzo

AU - Battaglia, Mario Alberto

AU - Gallo, Antonio

AU - Nedovic, Darko

AU - Lombardi, Emilio

AU - Spadera, Anna Pia

PY - 2015

Y1 - 2015

N2 - This cross-sectional study has investigated the diagnostic and therapeutic management of patients suffering from multiple sclerosis (MS) in the Campania Region (Italy). A survey involving all the reference centers for MS in Campania Region was conducted from March to August 2011. Centers responded to a web-administered questionnaire on management and clinical characteristics of MS patients. In the study period, 3263 patients (mean age 37 years, 66 % females) accessed the centers. Patients received a first diagnosis of MS in 161 cases (4.9 %). About 37 % of the subjects without a previous diagnosis came to the centers on their own initiative. All patients underwent a complete neurological examination and expanded disability status scale. The other most common investigations were magnetic resonance imaging (44.0 %) and evoked potentials (22.1 %). The number of treated patients was 2797 (87.1 %). The most used drugs were interferon b and glatiramer acetate. The time between diagnosis and initiation of therapy exceeded 6 months in 32 % of cases. Second-line drugs were under-used: 16 % of patients who might benefit from them show high clinical and radiological disease activity despite treatment with immunomodulant drugs. The MS care management of the surveyed centers showed consistent margins for improvement in 2011. Even though these data do not represent the current situation, they can be used to monitor improvements in MS care.

AB - This cross-sectional study has investigated the diagnostic and therapeutic management of patients suffering from multiple sclerosis (MS) in the Campania Region (Italy). A survey involving all the reference centers for MS in Campania Region was conducted from March to August 2011. Centers responded to a web-administered questionnaire on management and clinical characteristics of MS patients. In the study period, 3263 patients (mean age 37 years, 66 % females) accessed the centers. Patients received a first diagnosis of MS in 161 cases (4.9 %). About 37 % of the subjects without a previous diagnosis came to the centers on their own initiative. All patients underwent a complete neurological examination and expanded disability status scale. The other most common investigations were magnetic resonance imaging (44.0 %) and evoked potentials (22.1 %). The number of treated patients was 2797 (87.1 %). The most used drugs were interferon b and glatiramer acetate. The time between diagnosis and initiation of therapy exceeded 6 months in 32 % of cases. Second-line drugs were under-used: 16 % of patients who might benefit from them show high clinical and radiological disease activity despite treatment with immunomodulant drugs. The MS care management of the surveyed centers showed consistent margins for improvement in 2011. Even though these data do not represent the current situation, they can be used to monitor improvements in MS care.

UR - http://hdl.handle.net/10447/157524

M3 - Article

SP - -

JO - Neurological Sciences

JF - Neurological Sciences

SN - 1590-1874

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