The Fate of Nephrons in Congenital Obstructive Nephropathy: Adult Recovery is Limited by Nephron Number Despite Early Release of Obstruction

Maria Sergio, Carolina I. Galarreta, Michael S. Forbes, Michael S. Forbes, Maria Sergio, Barbara A. Thornhill, Robert L. Chevalier, Michael S. Forbes

Risultato della ricerca: Article

7 Citazioni (Scopus)

Abstract

Urinary tract obstruction and reduced nephron number often occur together as a result of maldevelopment of kidneys and urinary tract. We wished to determine the role of nephron number on the adaptation of remaining nephrons of mice subjected to neonatal partial unilateral ureteral obstruction (UUO) and followed through adulthood.
Lingua originaleEnglish
pagine (da-a)1463-1472
Numero di pagine10
RivistaTHE JOURNAL OF UROLOGY
Volume194
Stato di pubblicazionePublished - 2015

    Fingerprint

All Science Journal Classification (ASJC) codes

  • Urology

Cita questo

Sergio, M., Galarreta, C. I., Forbes, M. S., Forbes, M. S., Sergio, M., Thornhill, B. A., Chevalier, R. L., & Forbes, M. S. (2015). The Fate of Nephrons in Congenital Obstructive Nephropathy: Adult Recovery is Limited by Nephron Number Despite Early Release of Obstruction. THE JOURNAL OF UROLOGY, 194, 1463-1472.