TY - JOUR
T1 - THE EUROPEAN SLEEP APNOEA DATABASE (ESADA) -- Report from 22 European Sleep Laboratories
AU - Bonsignore, Maria Rosaria
AU - Parati, null
AU - Vrints, null
AU - Bonsignore, Marisa R.
AU - Mcnicholas, null
AU - Sliwinski, null
AU - Varoneckas, null
AU - Kvamme, null
AU - Tkacova, null
AU - Escourrou, null
AU - Schulz, null
AU - Vitols, null
AU - Montserrat, Josep M.
AU - Penzel, null
AU - Varoneckas, null
AU - Parati, Gianfranco
AU - Marrone, Oreste
AU - Riha, null
AU - Pretl, null
AU - Saaresranta, null
AU - Masa, null
AU - Marrone, null
AU - Fietze, null
AU - Hedner, null
AU - Penzel, null
AU - De Backer, null
AU - Rodenstein, null
AU - Grote, null
AU - Barbé, null
AU - Lombardi, Carolina
AU - Lavie, null
AU - Zielinski, null
PY - 2011
Y1 - 2011
N2 - The European Sleep Apnoea Database (ESADA) reflects a network of 22 sleep disorder centres in Europe enabled by a COST action B26 program. This ongoing project aims to describe differences in standard clinical care of patients with obstructive sleep apnoea (OSA) and to establish a resource for genetic research in this disorder. Patients with suspected OSA are consecutively included and followed up according to local clinical standards. Anthropometrics, medical history, medication, daytime symptoms and sleep data (polysomnography or cardiorespiratory polygraphy) are recorded in a structured web-based report form. 5103 patients (1426 females, age 51.8±12.6 years, 79.4% with AHI≥5 events·hr(-1)) were included from March 15, 2007 to August 1, 2009. Morbid obesity (BMI≥35 kg·m(-2)) was present in 21.1% of males and 28.6% of women. Cardiovascular, metabolic, and pulmonary comorbidities were frequent (49.1, 32.9 and 14.2%, respectively). Patients investigated with a polygraphic method had a lower AHI than those undergoing polysomnography (23.2±23.5 vs. 29.1±26.3 events·hour(-1), p<0.0001). The ESADA is a rapidly growing multicentric patient cohort that enables unique outcome research opportunities and genotyping. The first cross sectional analysis reveals a high prevalence of cardiovascular and metabolic morbidity in patients investigated for OSAS.
AB - The European Sleep Apnoea Database (ESADA) reflects a network of 22 sleep disorder centres in Europe enabled by a COST action B26 program. This ongoing project aims to describe differences in standard clinical care of patients with obstructive sleep apnoea (OSA) and to establish a resource for genetic research in this disorder. Patients with suspected OSA are consecutively included and followed up according to local clinical standards. Anthropometrics, medical history, medication, daytime symptoms and sleep data (polysomnography or cardiorespiratory polygraphy) are recorded in a structured web-based report form. 5103 patients (1426 females, age 51.8±12.6 years, 79.4% with AHI≥5 events·hr(-1)) were included from March 15, 2007 to August 1, 2009. Morbid obesity (BMI≥35 kg·m(-2)) was present in 21.1% of males and 28.6% of women. Cardiovascular, metabolic, and pulmonary comorbidities were frequent (49.1, 32.9 and 14.2%, respectively). Patients investigated with a polygraphic method had a lower AHI than those undergoing polysomnography (23.2±23.5 vs. 29.1±26.3 events·hour(-1), p<0.0001). The ESADA is a rapidly growing multicentric patient cohort that enables unique outcome research opportunities and genotyping. The first cross sectional analysis reveals a high prevalence of cardiovascular and metabolic morbidity in patients investigated for OSAS.
KW - European Sleep Apnoea Database
KW - comorbidity
KW - genetic
KW - multicentre cohort
KW - obstructive sleep apnoea syndrome
KW - European Sleep Apnoea Database
KW - comorbidity
KW - genetic
KW - multicentre cohort
KW - obstructive sleep apnoea syndrome
UR - http://hdl.handle.net/10447/58354
M3 - Article
SN - 0903-1936
VL - 38
SP - 635
EP - 642
JO - European Respiratory Journal
JF - European Respiratory Journal
ER -