TY - JOUR
T1 - The Clinical Picture of Uncomplicated Versus Complicated Diverticulitis of the Colon
AU - Aiello, Fabio
AU - Giorgetti, Gianmarco
AU - Tursi, Antonio
AU - Maiorano, Michele
AU - Brandimarte, Giovanni
AU - Elisei, Walter
PY - 2008
Y1 - 2008
N2 - Purpose There is no consensus about the correct definition of uncomplicated diverticulitis (UD) in clinical practice. We evaluated therefore whether clinical picture of UD differs from complicated diverticulitis (CD).Fifty consecutive eligible patients (21 males, 29 females, mean age 63.6 years, range 47–75 years) were studied.Symptoms, the inflammatory indices, and Computerized Tomography (CT) scan of the abdomen were assessed at the time of admission. Results Thirty-nine patients classified were affected by UD and 11 patients by CD. CDpatients showed more severe clinical picture than UD andrequired urgent Hospital admission. Conversely, most ofthe patients affected by UD were treated as outpatients. CD patients showed higher symptom scores than UD patients,except the parameter ‘‘diarrhea’’. All CD patients showed increases in all inflammatory indices. Conversely, all UDpatients showed increased ESR, CRP and fibrinogen, but WBC and a1-acid glycoprotein were increased in only a few cases. CT scan in CD patients always showed signs ofsevere colonic and pericolonic inflammation. Conversely, UD patients often showed moderate localized signs of inflammation without complication. Conclusions Clinical,laboratory, and radiological findings may easily differentiate uncomplicated from complicated diverticulitis of the colon. This integrated approach may be helpful in clinical settings.
AB - Purpose There is no consensus about the correct definition of uncomplicated diverticulitis (UD) in clinical practice. We evaluated therefore whether clinical picture of UD differs from complicated diverticulitis (CD).Fifty consecutive eligible patients (21 males, 29 females, mean age 63.6 years, range 47–75 years) were studied.Symptoms, the inflammatory indices, and Computerized Tomography (CT) scan of the abdomen were assessed at the time of admission. Results Thirty-nine patients classified were affected by UD and 11 patients by CD. CDpatients showed more severe clinical picture than UD andrequired urgent Hospital admission. Conversely, most ofthe patients affected by UD were treated as outpatients. CD patients showed higher symptom scores than UD patients,except the parameter ‘‘diarrhea’’. All CD patients showed increases in all inflammatory indices. Conversely, all UDpatients showed increased ESR, CRP and fibrinogen, but WBC and a1-acid glycoprotein were increased in only a few cases. CT scan in CD patients always showed signs ofsevere colonic and pericolonic inflammation. Conversely, UD patients often showed moderate localized signs of inflammation without complication. Conclusions Clinical,laboratory, and radiological findings may easily differentiate uncomplicated from complicated diverticulitis of the colon. This integrated approach may be helpful in clinical settings.
KW - Complicated diverticulitis
KW - Endoscopy
KW - Laboratory
KW - Radiology
KW - Uncomplicated diverticulitis.
KW - Complicated diverticulitis
KW - Endoscopy
KW - Laboratory
KW - Radiology
KW - Uncomplicated diverticulitis.
UR - http://hdl.handle.net/10447/38508
M3 - Article
VL - 53(9)
SP - 2474
EP - 2479
JO - American Journal of Digestive Diseases
JF - American Journal of Digestive Diseases
SN - 0002-9211
ER -