The Ciona intestinalis immune-related galectin genes (CiLgals-a and CiLgals-b) are expressed by the gastric epithelium

Daniela Parrinello, Aiti Vizzini, Nicolo' Parrinello, Matteo Cammarata, Maria Antonietta Sanfratello, Matteo Cammarata, Maria Antonietta Sanfratello, Lelia Testasecca, Daniela Parrinello, Nicolò Parrinello, Aiti Vizzini

Risultato della ricerca: Article

3 Citazioni (Scopus)

Abstract

The transcription of two Ciona intestinalis galectin genes (CiLgals-a and CiLgalseb) is uparegulated by LPSin the pharynxis (hemocytes, vessel epithelium, endostilar zones) which is retained the main organ ofthe immunity. In this ascidian, for the first time we show, by immunohistochemistry and in situ hybridizationmethods, that these two immune-related genes are expressed in the gastric epithelium ofnaïve ascidians, whereas the galectins appear to be only contained in the intestine columnar epithelium.In addition, according to previous results on the pharynx, the genes are also expressed and galectinsproduced by hemocytes scattered in the connective tissue surrounding the gut. The genes expression andgalectin localization in several tissues, including the previous findings on the transcription upregulation,the constitutive expression of these genes by endostylar zones and by the gastric epithelium suggest apotential multifunctional role of these galectins. In this respect, it is of interest to define where theCiLgals are normally found as related to the tissue functions. Such an approach should be a starting pointfor further investigations.
Lingua originaleEnglish
Numero di pagine7
RivistaDefault journal
Stato di pubblicazionePublished - 2016

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Galectins
stomach
epithelium
Genes
gene
Ascidiacea
Transcription
Tissue
hemocytes
genes
transcription (genetics)
gene expression
pharynx
immunity
Gene expression
connective tissues
immunohistochemistry
intestines
vessel
digestive system

All Science Journal Classification (ASJC) codes

  • Environmental Chemistry
  • Aquatic Science

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The Ciona intestinalis immune-related galectin genes (CiLgals-a and CiLgals-b) are expressed by the gastric epithelium. / Parrinello, Daniela; Vizzini, Aiti; Parrinello, Nicolo'; Cammarata, Matteo; Sanfratello, Maria Antonietta; Cammarata, Matteo; Sanfratello, Maria Antonietta; Testasecca, Lelia; Parrinello, Daniela; Parrinello, Nicolò; Vizzini, Aiti.

In: Default journal, 2016.

Risultato della ricerca: Article

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abstract = "The transcription of two Ciona intestinalis galectin genes (CiLgals-a and CiLgalseb) is uparegulated by LPSin the pharynxis (hemocytes, vessel epithelium, endostilar zones) which is retained the main organ ofthe immunity. In this ascidian, for the first time we show, by immunohistochemistry and in situ hybridizationmethods, that these two immune-related genes are expressed in the gastric epithelium ofna{\"i}ve ascidians, whereas the galectins appear to be only contained in the intestine columnar epithelium.In addition, according to previous results on the pharynx, the genes are also expressed and galectinsproduced by hemocytes scattered in the connective tissue surrounding the gut. The genes expression andgalectin localization in several tissues, including the previous findings on the transcription upregulation,the constitutive expression of these genes by endostylar zones and by the gastric epithelium suggest apotential multifunctional role of these galectins. In this respect, it is of interest to define where theCiLgals are normally found as related to the tissue functions. Such an approach should be a starting pointfor further investigations.",
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T1 - The Ciona intestinalis immune-related galectin genes (CiLgals-a and CiLgals-b) are expressed by the gastric epithelium

AU - Parrinello, Daniela

AU - Vizzini, Aiti

AU - Parrinello, Nicolo'

AU - Cammarata, Matteo

AU - Sanfratello, Maria Antonietta

AU - Cammarata, Matteo

AU - Sanfratello, Maria Antonietta

AU - Testasecca, Lelia

AU - Parrinello, Daniela

AU - Parrinello, Nicolò

AU - Vizzini, Aiti

PY - 2016

Y1 - 2016

N2 - The transcription of two Ciona intestinalis galectin genes (CiLgals-a and CiLgalseb) is uparegulated by LPSin the pharynxis (hemocytes, vessel epithelium, endostilar zones) which is retained the main organ ofthe immunity. In this ascidian, for the first time we show, by immunohistochemistry and in situ hybridizationmethods, that these two immune-related genes are expressed in the gastric epithelium ofnaïve ascidians, whereas the galectins appear to be only contained in the intestine columnar epithelium.In addition, according to previous results on the pharynx, the genes are also expressed and galectinsproduced by hemocytes scattered in the connective tissue surrounding the gut. The genes expression andgalectin localization in several tissues, including the previous findings on the transcription upregulation,the constitutive expression of these genes by endostylar zones and by the gastric epithelium suggest apotential multifunctional role of these galectins. In this respect, it is of interest to define where theCiLgals are normally found as related to the tissue functions. Such an approach should be a starting pointfor further investigations.

AB - The transcription of two Ciona intestinalis galectin genes (CiLgals-a and CiLgalseb) is uparegulated by LPSin the pharynxis (hemocytes, vessel epithelium, endostilar zones) which is retained the main organ ofthe immunity. In this ascidian, for the first time we show, by immunohistochemistry and in situ hybridizationmethods, that these two immune-related genes are expressed in the gastric epithelium ofnaïve ascidians, whereas the galectins appear to be only contained in the intestine columnar epithelium.In addition, according to previous results on the pharynx, the genes are also expressed and galectinsproduced by hemocytes scattered in the connective tissue surrounding the gut. The genes expression andgalectin localization in several tissues, including the previous findings on the transcription upregulation,the constitutive expression of these genes by endostylar zones and by the gastric epithelium suggest apotential multifunctional role of these galectins. In this respect, it is of interest to define where theCiLgals are normally found as related to the tissue functions. Such an approach should be a starting pointfor further investigations.

UR - http://hdl.handle.net/10447/225673

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