Thalamic stroke mimicking frontotemporal dementia: a case report

Riolo, M; Cusmano, I; Piccoli T

Risultato della ricerca: Other contribution

Abstract

Background: The behavioral variant of frontotemporal dementia (bvFTD) is characterized by changes of personality, social behavior and cognition and relies on a neurodegenerative process. However, vascular lesions affecting subcortical structures may result in a clinical syndrome resembling bvFTD. Objective: To describe a case of thalamic stroke resulting in frontal dementia. Case report: A 58-year-old man was referred to our hospital because of behavioral and cognitive changes formerly diagnosed as bvFTD. In 2010, he suddenly presented loss of consciousness and in the next days he developed amnesia, apathy and personality changes. Toxicological exams, CSF analysis and CT scan were normal at admission. Neuropsychological tests showed an impairment of executive functions and amnesia. He was referred to our Center in 2011. Behavioral disturbances and cognitive dysfunctions were already improved since the onset, and at six-month follow-up neuropsychological test showed a further recovery of cognitive functions. Brain MRI showed a left thalamic infarct. Conclusions: The sudden onset and the improvement of clinical signs suggest a vascular origin of the syndrome. The FTD-like picture is attributable to a disruption of the fronto-subcortical circuits at the level of the striatum or the anterior thalamic peduncle. Vascular dementia should be considered in differential diagnosis of bvFTD.
Lingua originaleEnglish
Stato di pubblicazionePublished - 2012

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Frontotemporal Dementia
Stroke
Amnesia
Neuropsychological Tests
Cognition
Blood Vessels
Personality
Apathy
Vascular Dementia
Unconsciousness
Social Behavior
Executive Function
Recovery of Function
Toxicology
Dementia
Differential Diagnosis
Brain

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Thalamic stroke mimicking frontotemporal dementia: a case report. / Riolo, M; Cusmano, I; Piccoli T.

2012, .

Risultato della ricerca: Other contribution

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abstract = "Background: The behavioral variant of frontotemporal dementia (bvFTD) is characterized by changes of personality, social behavior and cognition and relies on a neurodegenerative process. However, vascular lesions affecting subcortical structures may result in a clinical syndrome resembling bvFTD. Objective: To describe a case of thalamic stroke resulting in frontal dementia. Case report: A 58-year-old man was referred to our hospital because of behavioral and cognitive changes formerly diagnosed as bvFTD. In 2010, he suddenly presented loss of consciousness and in the next days he developed amnesia, apathy and personality changes. Toxicological exams, CSF analysis and CT scan were normal at admission. Neuropsychological tests showed an impairment of executive functions and amnesia. He was referred to our Center in 2011. Behavioral disturbances and cognitive dysfunctions were already improved since the onset, and at six-month follow-up neuropsychological test showed a further recovery of cognitive functions. Brain MRI showed a left thalamic infarct. Conclusions: The sudden onset and the improvement of clinical signs suggest a vascular origin of the syndrome. The FTD-like picture is attributable to a disruption of the fronto-subcortical circuits at the level of the striatum or the anterior thalamic peduncle. Vascular dementia should be considered in differential diagnosis of bvFTD.",
keywords = "dementia, stroke, frontotemporal dementia",
author = "{Riolo, M; Cusmano, I; Piccoli T} and Chiara Cupidi and Tommaso Piccoli and Sabrina Realmuto and Mazzola, {Maria Antonietta} and Simona Talamanca and Valentina Arnao and Antonio Cinturino",
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language = "English",
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T1 - Thalamic stroke mimicking frontotemporal dementia: a case report

AU - Riolo, M; Cusmano, I; Piccoli T

AU - Cupidi, Chiara

AU - Piccoli, Tommaso

AU - Realmuto, Sabrina

AU - Mazzola, Maria Antonietta

AU - Talamanca, Simona

AU - Arnao, Valentina

AU - Cinturino, Antonio

PY - 2012

Y1 - 2012

N2 - Background: The behavioral variant of frontotemporal dementia (bvFTD) is characterized by changes of personality, social behavior and cognition and relies on a neurodegenerative process. However, vascular lesions affecting subcortical structures may result in a clinical syndrome resembling bvFTD. Objective: To describe a case of thalamic stroke resulting in frontal dementia. Case report: A 58-year-old man was referred to our hospital because of behavioral and cognitive changes formerly diagnosed as bvFTD. In 2010, he suddenly presented loss of consciousness and in the next days he developed amnesia, apathy and personality changes. Toxicological exams, CSF analysis and CT scan were normal at admission. Neuropsychological tests showed an impairment of executive functions and amnesia. He was referred to our Center in 2011. Behavioral disturbances and cognitive dysfunctions were already improved since the onset, and at six-month follow-up neuropsychological test showed a further recovery of cognitive functions. Brain MRI showed a left thalamic infarct. Conclusions: The sudden onset and the improvement of clinical signs suggest a vascular origin of the syndrome. The FTD-like picture is attributable to a disruption of the fronto-subcortical circuits at the level of the striatum or the anterior thalamic peduncle. Vascular dementia should be considered in differential diagnosis of bvFTD.

AB - Background: The behavioral variant of frontotemporal dementia (bvFTD) is characterized by changes of personality, social behavior and cognition and relies on a neurodegenerative process. However, vascular lesions affecting subcortical structures may result in a clinical syndrome resembling bvFTD. Objective: To describe a case of thalamic stroke resulting in frontal dementia. Case report: A 58-year-old man was referred to our hospital because of behavioral and cognitive changes formerly diagnosed as bvFTD. In 2010, he suddenly presented loss of consciousness and in the next days he developed amnesia, apathy and personality changes. Toxicological exams, CSF analysis and CT scan were normal at admission. Neuropsychological tests showed an impairment of executive functions and amnesia. He was referred to our Center in 2011. Behavioral disturbances and cognitive dysfunctions were already improved since the onset, and at six-month follow-up neuropsychological test showed a further recovery of cognitive functions. Brain MRI showed a left thalamic infarct. Conclusions: The sudden onset and the improvement of clinical signs suggest a vascular origin of the syndrome. The FTD-like picture is attributable to a disruption of the fronto-subcortical circuits at the level of the striatum or the anterior thalamic peduncle. Vascular dementia should be considered in differential diagnosis of bvFTD.

KW - dementia, stroke, frontotemporal dementia

UR - http://hdl.handle.net/10447/72697

M3 - Other contribution

ER -