TERAPIA CON STATINE IN PAZIENTI SICILIANI AFFETTI DA IPERLIPIDEMIA FAMILIARE COMBINATA

Angelo Baldassare Cefalu', Carlo Maria Barbagallo, Maurizio Averna, Maurizio R. Averna, Alberto Notarbartolo, Alessandra Foresta, Emanuela Fertitta, Francesca Fayer, Maria Concetta Gueli, Marina Pomilla, Salvatore Amato

Risultato della ricerca: Articlepeer review

Abstract

Familial combined hyperlipidemia (FCHL) is the most frequent genetic hyperlipidemia. FHCL is associated withhigh prevalence of cardiovascular disease. In this study we selected 208 patients affected by FHCL and evaluatedthe efficacy of the lipid-lowering statin therapy using different statins available in the market. The resultsshow that the percent of patients reaching the therapeutic goal ranges from 19.7 % (LDL-C <100 mg/dL) to50.9% (LDL-C <130 mg/dL) and from 16.9 % (non HDL-C <130 mg/dL) to 46.6 % (non HDL-C <160 mg/dL)according to the different ATPIII-NCEP-guidelines cut offs. In conclusion the statin monotherapy is only partlyeffective in the management of FCHL therapy
Lingua originaleItalian
pagine (da-a)123-129
Numero di pagine7
RivistaTrends in Medicine
Volume7
Stato di pubblicazionePublished - 2007

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Pharmacology (medical)

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