TERAPIA CON STATINE IN PAZIENTI SICILIANI AFFETTI DA IPERLIPIDEMIA FAMILIARE COMBINATA

Angelo Baldassare Cefalu', Carlo Maria Barbagallo, Maurizio Averna, Maurizio R. Averna, Alberto Notarbartolo, Alessandra Foresta, Emanuela Fertitta, Francesca Fayer, Maria Concetta Gueli, Marina Pomilla, Salvatore Amato

Risultato della ricerca: Article

Abstract

Familial combined hyperlipidemia (FCHL) is the most frequent genetic hyperlipidemia. FHCL is associated withhigh prevalence of cardiovascular disease. In this study we selected 208 patients affected by FHCL and evaluatedthe efficacy of the lipid-lowering statin therapy using different statins available in the market. The resultsshow that the percent of patients reaching the therapeutic goal ranges from 19.7 % (LDL-C <100 mg/dL) to50.9% (LDL-C <130 mg/dL) and from 16.9 % (non HDL-C <130 mg/dL) to 46.6 % (non HDL-C <160 mg/dL)according to the different ATPIII-NCEP-guidelines cut offs. In conclusion the statin monotherapy is only partlyeffective in the management of FCHL therapy
Lingua originaleItalian
pagine (da-a)123-129
Numero di pagine7
RivistaTrends in Medicine
Volume7
Stato di pubblicazionePublished - 2007

All Science Journal Classification (ASJC) codes

  • Internal Medicine
  • Pharmacology (medical)

Cita questo

TERAPIA CON STATINE IN PAZIENTI SICILIANI AFFETTI DA IPERLIPIDEMIA FAMILIARE COMBINATA. / Cefalu', Angelo Baldassare; Barbagallo, Carlo Maria; Averna, Maurizio; Averna, Maurizio R.; Notarbartolo, Alberto; Foresta, Alessandra; Fertitta, Emanuela; Fayer, Francesca; Gueli, Maria Concetta; Pomilla, Marina; Amato, Salvatore.

In: Trends in Medicine, Vol. 7, 2007, pag. 123-129.

Risultato della ricerca: Article

Cefalu', AB, Barbagallo, CM, Averna, M, Averna, MR, Notarbartolo, A, Foresta, A, Fertitta, E, Fayer, F, Gueli, MC, Pomilla, M & Amato, S 2007, 'TERAPIA CON STATINE IN PAZIENTI SICILIANI AFFETTI DA IPERLIPIDEMIA FAMILIARE COMBINATA', Trends in Medicine, vol. 7, pagg. 123-129.
Cefalu', Angelo Baldassare ; Barbagallo, Carlo Maria ; Averna, Maurizio ; Averna, Maurizio R. ; Notarbartolo, Alberto ; Foresta, Alessandra ; Fertitta, Emanuela ; Fayer, Francesca ; Gueli, Maria Concetta ; Pomilla, Marina ; Amato, Salvatore. / TERAPIA CON STATINE IN PAZIENTI SICILIANI AFFETTI DA IPERLIPIDEMIA FAMILIARE COMBINATA. In: Trends in Medicine. 2007 ; Vol. 7. pagg. 123-129.
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abstract = "Familial combined hyperlipidemia (FCHL) is the most frequent genetic hyperlipidemia. FHCL is associated withhigh prevalence of cardiovascular disease. In this study we selected 208 patients affected by FHCL and evaluatedthe efficacy of the lipid-lowering statin therapy using different statins available in the market. The resultsshow that the percent of patients reaching the therapeutic goal ranges from 19.7 {\%} (LDL-C <100 mg/dL) to50.9{\%} (LDL-C <130 mg/dL) and from 16.9 {\%} (non HDL-C <130 mg/dL) to 46.6 {\%} (non HDL-C <160 mg/dL)according to the different ATPIII-NCEP-guidelines cut offs. In conclusion the statin monotherapy is only partlyeffective in the management of FCHL therapy",
author = "Cefalu', {Angelo Baldassare} and Barbagallo, {Carlo Maria} and Maurizio Averna and Averna, {Maurizio R.} and Alberto Notarbartolo and Alessandra Foresta and Emanuela Fertitta and Francesca Fayer and Gueli, {Maria Concetta} and Marina Pomilla and Salvatore Amato",
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T1 - TERAPIA CON STATINE IN PAZIENTI SICILIANI AFFETTI DA IPERLIPIDEMIA FAMILIARE COMBINATA

AU - Cefalu', Angelo Baldassare

AU - Barbagallo, Carlo Maria

AU - Averna, Maurizio

AU - Averna, Maurizio R.

AU - Notarbartolo, Alberto

AU - Foresta, Alessandra

AU - Fertitta, Emanuela

AU - Fayer, Francesca

AU - Gueli, Maria Concetta

AU - Pomilla, Marina

AU - Amato, Salvatore

PY - 2007

Y1 - 2007

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AB - Familial combined hyperlipidemia (FCHL) is the most frequent genetic hyperlipidemia. FHCL is associated withhigh prevalence of cardiovascular disease. In this study we selected 208 patients affected by FHCL and evaluatedthe efficacy of the lipid-lowering statin therapy using different statins available in the market. The resultsshow that the percent of patients reaching the therapeutic goal ranges from 19.7 % (LDL-C <100 mg/dL) to50.9% (LDL-C <130 mg/dL) and from 16.9 % (non HDL-C <130 mg/dL) to 46.6 % (non HDL-C <160 mg/dL)according to the different ATPIII-NCEP-guidelines cut offs. In conclusion the statin monotherapy is only partlyeffective in the management of FCHL therapy

UR - http://hdl.handle.net/10447/15645

M3 - Article

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EP - 129

JO - Trends in Medicine

JF - Trends in Medicine

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