Temporal variation in the distribution of type-1 human astrovirus lineages in a settled population over 14 years

Giovanni Giammanco, Simona De Grazia, Vito Martella, Ákos Gellért, Krisztián Bányai, Floriana Bonura, Sandra Marineo

Risultato della ricerca: Articlepeer review

8 Citazioni (Scopus)

Abstract

Human astroviruses (HAstVs) are important enteric pathogens that are genetically and antigenically heterogeneous and can be classified into eight sero/genotypes (HAstV-1 to -8) and different lineages within each HAstV type. This study describes the genetic diversity of HAstVs circulating in southern Italy over 14 years. Molecular analysis of HAstV-1 strains showed that three different lineages (1a, 1b and 1d) of the predominant genotype were circulating during the study period. The study of an archival collection of HAstV strains offers a unique opportunity to evaluate the patterns of variation of HAstV infections over the years and to correlate the observed epidemiological changes to the genetic variability of HAstVs.
Lingua originaleEnglish
pagine (da-a)1633-1637
Numero di pagine5
RivistaArchives of Virology
Volume161
Stato di pubblicazionePublished - 2016

All Science Journal Classification (ASJC) codes

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