Temporal trends in chronic total occlusion interventions in Europe: 17626 procedures from the European Registry of Chronic total occlusion

Alfredo Ruggero Galassi, Thierry Lefèvre, Georgios Giannopoulos, Evald H. Christiansen, Nicolas Boudou, Bernward Lauer, Alfredo R. Galassi, Kambis Mashayekhi, Spyridon Deftereos, Nikolaos V. Konstantinidis, Javier Escaned, Alexandre Avran, Markus Meyer-Geßner, Joachim H. Buettner, Roberto Garbo, Lefteris Angelis, Simon Elhadad, Mauro Carlino, Omer Goktekin, Georgios SianosAlexander Bufe, Alfredo R. Galassi, Yves Louvard, Carlo Di Mario, Gerald S. Werner, Nicolaus Reifart, David Hildick-Smith

Risultato della ricerca: Articlepeer review

72 Citazioni (Scopus)


BACKGROUND: The study focuses on the evolution of practice, procedural outcomes, and in-hospital complications of chronic total occlusion percutaneous coronary intervention in Europe. METHODS AND RESULTS: Data from 17 626 procedures enrolled in European Registry of Chronic Total Occlusion between January 2008 and June 2015 were assessed. The mean patient age was 63.9±10.9 years; 85% were men. Procedural success increased from 79.7% to 89.3% through the study period. Patients enrolled during the years had increasing comorbidities and lesion complexity (J-CTO score [Multicenter CTO Registry of Japan] increased from 1.76±1.03 in 2008 to 2.17±0.91 in 2015; P for trend, <0.001). Retrograde approach utilization steadily increased from 10.1% in 2008 to 29.9% in 2015 (P for trend, <0.001). Antegrade dissection reentry adoption was low, not exceeding 5.5%. In-hospital mortality decreased during the study period from 0.4% to 0.1% (P for trend, <0.001), whereas in-hospital complication rates remained essentially unchanged, in the range 4.4% to 5.2% (P for trend, 0.390). CONCLUSIONS: Chronic total occlusion percutaneous coronary intervention has shown a steady increase in procedural success rate over time, with unchanged complication rates, despite the increasing complexity of the lesions attempted. The J-CTO score predictive value for procedural success was low for the entire registry and had no predictive ability for the retrograde approach.
Lingua originaleEnglish
pagine (da-a)e006229-
Numero di pagine11
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

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