TY - JOUR
T1 - Temperature-induced self-assembly of degalactosylated xyloglucan at low concentration
AU - Dispenza, Clelia
AU - Todaro, Simona
AU - Sabatino, Maria Antonietta
AU - Ortore, Maria Grazia
AU - San Biagio, Pier Luigi
AU - Passantino, Rosa
AU - Bulone, Donatella
PY - 2015
Y1 - 2015
N2 - Xyloglucan is a natural polysaccharide having a cellulose-like backbone and hydroxyl groups-rich side-chains. In its native form the polymer is water-soluble and forms gel only in presence of selected co-solutes. When a given fraction of galactosyl residues are removed by enzymatic reaction, the polymer acquires the ability to form a gel in aqueous solution at physiological temperatures, a property of great interest for biomedical/pharmaceutical applications. This work presents data on the effect of a temperature increase on degalactosylated xyloglucan dispersed in water at concentration low enough not to run into macroscopic gelation. Results obtained over a wide interval of length scales show that, on increasing temperature, individual polymer chains and pre-existing clusters self-assemble into larger structures. The process implies a structural rearrangement over a few nanometers scale and an increase of dynamics homogeneity. The relation of these findings to coil-globule transition and phase separation is discussed.
AB - Xyloglucan is a natural polysaccharide having a cellulose-like backbone and hydroxyl groups-rich side-chains. In its native form the polymer is water-soluble and forms gel only in presence of selected co-solutes. When a given fraction of galactosyl residues are removed by enzymatic reaction, the polymer acquires the ability to form a gel in aqueous solution at physiological temperatures, a property of great interest for biomedical/pharmaceutical applications. This work presents data on the effect of a temperature increase on degalactosylated xyloglucan dispersed in water at concentration low enough not to run into macroscopic gelation. Results obtained over a wide interval of length scales show that, on increasing temperature, individual polymer chains and pre-existing clusters self-assemble into larger structures. The process implies a structural rearrangement over a few nanometers scale and an increase of dynamics homogeneity. The relation of these findings to coil-globule transition and phase separation is discussed.
KW - Condensed Matter Physics
KW - Materials Chemistry2506 Metals and Alloys
KW - Physical and Theoretical Chemistry
KW - Polymers and Plastics
KW - biopolymers
KW - self-assembly
KW - stimuli-sensitive polymers
KW - supramolecular structure
KW - Condensed Matter Physics
KW - Materials Chemistry2506 Metals and Alloys
KW - Physical and Theoretical Chemistry
KW - Polymers and Plastics
KW - biopolymers
KW - self-assembly
KW - stimuli-sensitive polymers
KW - supramolecular structure
UR - http://hdl.handle.net/10447/202925
UR - http://onlinelibrary.wiley.com/journal/10.1002/(ISSN)1099-0488
M3 - Article
VL - 53
SP - 1727
EP - 1735
JO - JOURNAL OF POLYMER SCIENCE. PART B, POLYMER PHYSICS
JF - JOURNAL OF POLYMER SCIENCE. PART B, POLYMER PHYSICS
SN - 0887-6266
ER -