Task force on: 'Early markers of atherosclerosis: influence of age and sex'

Salvatore Novo, Pietro Scicchitano, Michele Gesualdo, Marco Matteo Ciccone, Pasquale Palmiero, Anna Vittoria Mattioli, Elene Bilianou, Elene Bilianou, Lorenzo Ghiadoni, Annapaola Zito, Massimo Salvetti, Alberto Balbarini, Roberto Pedrinelli, Marco Metra

    Risultato della ricerca: Articlepeer review

    55 Citazioni (Scopus)


    Atherosclerosis and its complications are the most important causes of death all over the world, especially in Western countries. Diet habits, modern stress life, smoking, sedentary way of life and an involvement of genetic pattern of individuals lead to a sure degeneration of quality of life increasing the risk of atherosclerosis development. For this reason, the main purpose of actual medicine is to identify all the markers that could allow the physicians to evaluate the first moments of the development of this dangerous pathological process. The aim is to reduce the speed of its evolution, trying to delay indefinitely the risk coming from the morphological alterations of the vessels. 'Endothelium function' could allow physicians to detect the first moment of the natural history of atherosclerosis process. Its impairment is the first step in the degeneration of vascular structures. Many methods [flow-mediated vasodilatation (FMD); antero-posterior abdominal aorta diameter (APAO); intima-media thickness of the common carotid artery (CCA-IMT); arterial stiffness; and so on] try to evaluate its function, but many limitations come from general population characteristics. A standardization of the methods should take into account individuals' peculiarities. Two elements, not modifiable, should be taken into account for vascular evaluation: age and sex. The aim of this review is to outline the linkage among age, sex and instrumental evaluation of patients considered for a noninvasive assessment of their cardiovascular risk profile
    Lingua originaleEnglish
    pagine (da-a)757-766
    Numero di pagine10
    RivistaJournal of Cardiovascular Medicine
    Stato di pubblicazionePublished - 2013

    All Science Journal Classification (ASJC) codes

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