Synthesis of the New Ring System 2-Oxo-[1,4]oxazino[3,2-e]indole, Heteroanalogue of Angelicin

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Abstract

A series of 2-oxo-[1,4]oxazino[3,2-e ]indoles, heteroanalogues of Angelicin, have been synthesized by a multistep sequence consisting of the annelation of the oxazine ring on the indole moiety. The phototoxicity and the antiproliferative activity of the new derivatives were investigated.
Lingua originaleEnglish
pagine (da-a)4182-4184
Numero di pagine3
RivistaTetrahedron Letters
Volume50
Stato di pubblicazionePublished - 2009

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All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

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