Synthesis of isoindolo[1,4]benzoxazinone and isoindolo[1,5]benzoxazepine: two new ring systems of pharmaceutical interest

Risultato della ricerca: Articlepeer review

25 Citazioni (Scopus)

Abstract

Abstract Two new ring systems, isoindolo[1,4]benzoxazinone and isoindolo[1,5]benzoxazepine, were conveniently synthesized through cyclization of suitably substituted isoindole derivatives. Some of the new compounds exhibited antiproliferative activity against a wide range of human tumor cell lines with GI50 mean values at low micromolar level (3.72-5.13 μM).
Lingua originaleEnglish
pagine (da-a)7332-7338
Numero di pagine7
RivistaTetrahedron
Volume71
Stato di pubblicazionePublished - 2015

All Science Journal Classification (ASJC) codes

  • ???subjectarea.asjc.1300.1303???
  • ???subjectarea.asjc.3000.3002???
  • ???subjectarea.asjc.1600.1605???

Fingerprint

Entra nei temi di ricerca di 'Synthesis of isoindolo[1,4]benzoxazinone and isoindolo[1,5]benzoxazepine: two new ring systems of pharmaceutical interest'. Insieme formano una fingerprint unica.

Cita questo