Synthesis of 4(5)-phenacyl-imidazoles from isoxazole side-chainrearrangements

Risultato della ricerca: Articlepeer review

11 Citazioni (Scopus)


A novel base-induced rearrangement of isoxazoles into imidazole derivatives is reported. In theisoxazole series, this represents the first example of a three-atom side-chain rearrangementinvolving a CNC sequence. The reactions are carried out under nitrogen and produced2-aryl-4(5)-phenacyl-5(4)-phenyl-imidazoles in high yields. In the presence of oxygen, a cascaderearrangement-oxidation reaction sequence was observed and imidazole derivatives bearing an oxidizedside-chain were isolated.
Lingua originaleEnglish
pagine (da-a)491-496
Numero di pagine6
Stato di pubblicazionePublished - 2011

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

Fingerprint Entra nei temi di ricerca di 'Synthesis of 4(5)-phenacyl-imidazoles from isoxazole side-chainrearrangements'. Insieme formano una fingerprint unica.

Cita questo