Synthesis of 2,4,6-trisubstituted tetrahydropyrans via 6-exo selenoetherification of unsaturated alcohols

Serena Riela, Renato Noto, Michelangelo Gruttadauria, Serena Riela, Michelangelo Gruttadauria, Renato Noto, Carmela Aprile, Carmela Aprile

Risultato della ricerca: Articlepeer review

29 Citazioni (Scopus)

Abstract

Stereoselectivity, regioselectivity and yields in the 6-exo selenoetherification of four unsaturated diols were found to depend on the stereochemistry of the diols and on the presence of an oxygen atom close to the intermediate seleniranium ring. Silica gel was useful in order to obtain good yields. Reactions performed both under kinetic and thermodynamic control led to the same products.Stereoselectivity, regioselectivity and yields in the 6-exo selenoetherification of four unsaturated diols were found to depend on several factors such as the stereochemistry of the diols, the nature of the R group, the nature of the counter anion of the PhSe+ species and the presence of silica gel.
Lingua originaleEnglish
pagine (da-a)2213-2215
Numero di pagine3
RivistaTetrahedron Letters
Volume42
Stato di pubblicazionePublished - 2001

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Drug Discovery
  • Organic Chemistry

Fingerprint Entra nei temi di ricerca di 'Synthesis of 2,4,6-trisubstituted tetrahydropyrans via 6-exo selenoetherification of unsaturated alcohols'. Insieme formano una fingerprint unica.

Cita questo