TY - JOUR
T1 - Synthesis and characterization of new polyamino-cyclodextrin materials
AU - D'Anna, Francesca
AU - Noto, Renato
AU - Riela, Serena
AU - Lo Meo, Paolo Maria Giuseppe
AU - Gruttadauria, Michelangelo
PY - 2012
Y1 - 2012
N2 - With the aim of the synthesis of chemically modified cyclodextrins bearing polyamine pendant groups, potentially useful as capping agents for the preparation of nanosized metal systems or as auxiliaries for gene transfection, the reaction between the heptakis-(6-iodo)-(6-deoxy)-b-cyclodextrin and various polyamines has been explored. This synthetic approach allows obtaining materials constituted by mixtures of cyclodextrins, having different degrees of substitution, which were satisfactorilycharacterized by means of various complementary techniques (ESI-MS, NMR, potentiometric titration).The products obtained were successfully subjected to preliminary tests for their binding abilities towards suitable organic guests and as capping agents for the preparation of stable silver nanoparticles.
AB - With the aim of the synthesis of chemically modified cyclodextrins bearing polyamine pendant groups, potentially useful as capping agents for the preparation of nanosized metal systems or as auxiliaries for gene transfection, the reaction between the heptakis-(6-iodo)-(6-deoxy)-b-cyclodextrin and various polyamines has been explored. This synthetic approach allows obtaining materials constituted by mixtures of cyclodextrins, having different degrees of substitution, which were satisfactorilycharacterized by means of various complementary techniques (ESI-MS, NMR, potentiometric titration).The products obtained were successfully subjected to preliminary tests for their binding abilities towards suitable organic guests and as capping agents for the preparation of stable silver nanoparticles.
KW - ESI-MS mass spectrometry
KW - Gene transfection
KW - Modified cyclodextrins
KW - Polarimetry
KW - Potentiometric titration
KW - Silver nanoparticles
KW - ESI-MS mass spectrometry
KW - Gene transfection
KW - Modified cyclodextrins
KW - Polarimetry
KW - Potentiometric titration
KW - Silver nanoparticles
UR - http://hdl.handle.net/10447/61978
M3 - Article
VL - 347
SP - 32
EP - 39
JO - Carbohydrate Research
JF - Carbohydrate Research
SN - 0008-6215
ER -