Synthesis and Antiproliferative Activity of [1,2,4]triazino[4,3-a]indoles

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Abstract

A series of [1,2,4]triazino[4,3-a]indoles was prepared in good yield by reacting 2-diazo-3-ethoxycarbonylindole with methylene active compounds. Derivatives of the title ring system were tested against a panel of 60 human tumor cell lines, and showed inhibitory activity against a wide range of cancer cell lines at micromolar concentration.
Lingua originaleEnglish
pagine (da-a)3775-3780
Numero di pagine6
RivistaAnticancer Research
Volume24
Stato di pubblicazionePublished - 2004

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.1300.1306???

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