TY - JOUR
T1 - Synthesis and Antiproliferative Activity of [1,2,4]triazino[4,3-a]indoles
AU - Lauria, Antonino
AU - Barraja, Paola
AU - Almerico, Anna Maria
AU - Cirrincione, Girolamo
AU - Montalbano, Alessandra
AU - Dattolo, Gaetano
AU - Diana, Patrizia
AU - Cirrincione, Girolamo
PY - 2004
Y1 - 2004
N2 - A series of [1,2,4]triazino[4,3-a]indoles was prepared in good yield by reacting 2-diazo-3-ethoxycarbonylindole with methylene active compounds. Derivatives of the title ring system were tested against a panel of 60 human tumor cell lines, and showed inhibitory activity against a wide range of cancer cell lines at micromolar concentration.
AB - A series of [1,2,4]triazino[4,3-a]indoles was prepared in good yield by reacting 2-diazo-3-ethoxycarbonylindole with methylene active compounds. Derivatives of the title ring system were tested against a panel of 60 human tumor cell lines, and showed inhibitory activity against a wide range of cancer cell lines at micromolar concentration.
UR - http://hdl.handle.net/10447/32873
UR - http://ar.iiarjournals.org/content/24/6/3775.abstract
M3 - Article
VL - 24
SP - 3775
EP - 3780
JO - Anticancer Research
JF - Anticancer Research
SN - 0250-7005
ER -