Suspected cutaneous leishmaniasis in a sample of Western Sicily residents: what correlation with occupation?

Emanuele Amodio, Giuseppe Pistone, Maria Rita Bongiorno, Maria Gabriella Verso, Diego Picciotto, Emanuele Amodio, Antonella Migliazzo, Fabrizio Vitale, Federica Bruno, Germano Castelli

Risultato della ricerca: Article

Abstract

Background: Leishmaniasis is a widespread infectious disease, but there is not much information about its prevalence in high risk occupational categories. Objectives: Te aim of this study is to assess the prevalence of Leishmaniaimmunological positivity in human skin tissues collected from subjects living in Western Sicily, with suspected cutaneous Leishmania infection, in order to explore the risk possibly related to occupation. Methods: 318 consecutivesubjects (M/F ratio=1.0, mean age=40±25.4 years), attending the Dermatology Department of the University of Palermo Hospital from 2013 to 2015, without any previous history of Leishmania infection and performing variousoccupations, were included. Parasite isolation and PCR-RT test on skin scrapings were performed to evaluate the immunological status; all data were analyzed by the chi square test, comparing all positive results from the differentprovinces. Results: 81 (50.9%) out of 159 females and 79 (49.7%) out of 159 males were found PCR-RT positive to Leishmania infantum, with a higher risk in the Agrigento district (p<0.001) and in subjects living in rural areas (p=0.0038), regardless of the type of work performed. Te observed animal leishmaniasis prevalence in the same areas shows the endemic status of the disease in Sicily. Conclusions: Although based on a relatively small sample, our study shows that cutaneous leishmaniasis represents a health care problem with a medical and social impact in Western Sicily. An active surveillance system and the establishment of diagnosis and treatment centres could be usefulin controlling this public health problem.
Lingua originaleEnglish
pagine (da-a)123-129
Numero di pagine7
RivistaDefault journal
Volume108:2
Stato di pubblicazionePublished - 2017

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Sicily
Cutaneous Leishmaniasis
Occupations
Leishmaniasis
Leishmania
Leishmania infantum
Endemic Diseases
Polymerase Chain Reaction
Skin
Chi-Square Distribution
Dermatology
Infection
Skin Tests
Social Change
Communicable Diseases
Parasites
Public Health
Delivery of Health Care

All Science Journal Classification (ASJC) codes

  • Public Health, Environmental and Occupational Health

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Suspected cutaneous leishmaniasis in a sample of Western Sicily residents: what correlation with occupation? / Amodio, Emanuele; Pistone, Giuseppe; Bongiorno, Maria Rita; Verso, Maria Gabriella; Picciotto, Diego; Amodio, Emanuele; Migliazzo, Antonella; Vitale, Fabrizio; Bruno, Federica; Castelli, Germano.

In: Default journal, Vol. 108:2, 2017, pag. 123-129.

Risultato della ricerca: Article

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title = "Suspected cutaneous leishmaniasis in a sample of Western Sicily residents: what correlation with occupation?",
abstract = "Background: Leishmaniasis is a widespread infectious disease, but there is not much information about its prevalence in high risk occupational categories. Objectives: Te aim of this study is to assess the prevalence of Leishmaniaimmunological positivity in human skin tissues collected from subjects living in Western Sicily, with suspected cutaneous Leishmania infection, in order to explore the risk possibly related to occupation. Methods: 318 consecutivesubjects (M/F ratio=1.0, mean age=40±25.4 years), attending the Dermatology Department of the University of Palermo Hospital from 2013 to 2015, without any previous history of Leishmania infection and performing variousoccupations, were included. Parasite isolation and PCR-RT test on skin scrapings were performed to evaluate the immunological status; all data were analyzed by the chi square test, comparing all positive results from the differentprovinces. Results: 81 (50.9{\%}) out of 159 females and 79 (49.7{\%}) out of 159 males were found PCR-RT positive to Leishmania infantum, with a higher risk in the Agrigento district (p<0.001) and in subjects living in rural areas (p=0.0038), regardless of the type of work performed. Te observed animal leishmaniasis prevalence in the same areas shows the endemic status of the disease in Sicily. Conclusions: Although based on a relatively small sample, our study shows that cutaneous leishmaniasis represents a health care problem with a medical and social impact in Western Sicily. An active surveillance system and the establishment of diagnosis and treatment centres could be usefulin controlling this public health problem.",
author = "Emanuele Amodio and Giuseppe Pistone and Bongiorno, {Maria Rita} and Verso, {Maria Gabriella} and Diego Picciotto and Emanuele Amodio and Antonella Migliazzo and Fabrizio Vitale and Federica Bruno and Germano Castelli",
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T1 - Suspected cutaneous leishmaniasis in a sample of Western Sicily residents: what correlation with occupation?

AU - Amodio, Emanuele

AU - Pistone, Giuseppe

AU - Bongiorno, Maria Rita

AU - Verso, Maria Gabriella

AU - Picciotto, Diego

AU - Amodio, Emanuele

AU - Migliazzo, Antonella

AU - Vitale, Fabrizio

AU - Bruno, Federica

AU - Castelli, Germano

PY - 2017

Y1 - 2017

N2 - Background: Leishmaniasis is a widespread infectious disease, but there is not much information about its prevalence in high risk occupational categories. Objectives: Te aim of this study is to assess the prevalence of Leishmaniaimmunological positivity in human skin tissues collected from subjects living in Western Sicily, with suspected cutaneous Leishmania infection, in order to explore the risk possibly related to occupation. Methods: 318 consecutivesubjects (M/F ratio=1.0, mean age=40±25.4 years), attending the Dermatology Department of the University of Palermo Hospital from 2013 to 2015, without any previous history of Leishmania infection and performing variousoccupations, were included. Parasite isolation and PCR-RT test on skin scrapings were performed to evaluate the immunological status; all data were analyzed by the chi square test, comparing all positive results from the differentprovinces. Results: 81 (50.9%) out of 159 females and 79 (49.7%) out of 159 males were found PCR-RT positive to Leishmania infantum, with a higher risk in the Agrigento district (p<0.001) and in subjects living in rural areas (p=0.0038), regardless of the type of work performed. Te observed animal leishmaniasis prevalence in the same areas shows the endemic status of the disease in Sicily. Conclusions: Although based on a relatively small sample, our study shows that cutaneous leishmaniasis represents a health care problem with a medical and social impact in Western Sicily. An active surveillance system and the establishment of diagnosis and treatment centres could be usefulin controlling this public health problem.

AB - Background: Leishmaniasis is a widespread infectious disease, but there is not much information about its prevalence in high risk occupational categories. Objectives: Te aim of this study is to assess the prevalence of Leishmaniaimmunological positivity in human skin tissues collected from subjects living in Western Sicily, with suspected cutaneous Leishmania infection, in order to explore the risk possibly related to occupation. Methods: 318 consecutivesubjects (M/F ratio=1.0, mean age=40±25.4 years), attending the Dermatology Department of the University of Palermo Hospital from 2013 to 2015, without any previous history of Leishmania infection and performing variousoccupations, were included. Parasite isolation and PCR-RT test on skin scrapings were performed to evaluate the immunological status; all data were analyzed by the chi square test, comparing all positive results from the differentprovinces. Results: 81 (50.9%) out of 159 females and 79 (49.7%) out of 159 males were found PCR-RT positive to Leishmania infantum, with a higher risk in the Agrigento district (p<0.001) and in subjects living in rural areas (p=0.0038), regardless of the type of work performed. Te observed animal leishmaniasis prevalence in the same areas shows the endemic status of the disease in Sicily. Conclusions: Although based on a relatively small sample, our study shows that cutaneous leishmaniasis represents a health care problem with a medical and social impact in Western Sicily. An active surveillance system and the establishment of diagnosis and treatment centres could be usefulin controlling this public health problem.

UR - http://hdl.handle.net/10447/226109

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