Surveillance of human astrovirus circulation in Italy 2002-2005: emergence of lineage 2c strains

Maria Angela Platia, Claudia Colomba, Simona De Grazia, Giovanni Giammanco, Vito Martella

Risultato della ricerca: Article

25 Citazioni (Scopus)

Abstract

By screening faecal samples collected over four consecutive years (2002-2005) from hospitalized children with diarrhoea in Palermo, Italy, astroviruses (HAstVs) were detected in 3.95% of the patients. The predominant type circulating was HAstV-1 but, in 2002, only HAstV-2 and -4 were identified. Interestingly, the HAstVs-2 detected appeared to be consistently different in 5' end of their open reading frame 2 from the previously described subtypes. These novel type 2 strains were included in a new 2c lineage based on the phylogenetic analysis and the presence of nine peculiar substitutions.
Lingua originaleEnglish
pagine (da-a)97-101
Numero di pagine5
RivistaClinical Microbiology and Infection
Volume17
Stato di pubblicazionePublished - 2011

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Mamastrovirus
Hospitalized Child
Italy
Open Reading Frames
Diarrhea

All Science Journal Classification (ASJC) codes

  • Microbiology (medical)
  • Infectious Diseases

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Surveillance of human astrovirus circulation in Italy 2002-2005: emergence of lineage 2c strains. / Platia, Maria Angela; Colomba, Claudia; De Grazia, Simona; Giammanco, Giovanni; Martella, Vito.

In: Clinical Microbiology and Infection, Vol. 17, 2011, pag. 97-101.

Risultato della ricerca: Article

Platia, MA, Colomba, C, De Grazia, S, Giammanco, G & Martella, V 2011, 'Surveillance of human astrovirus circulation in Italy 2002-2005: emergence of lineage 2c strains', Clinical Microbiology and Infection, vol. 17, pagg. 97-101.
Platia MA, Colomba C, De Grazia S, Giammanco G, Martella V. Surveillance of human astrovirus circulation in Italy 2002-2005: emergence of lineage 2c strains. Clinical Microbiology and Infection. 2011;17:97-101.
Platia, Maria Angela ; Colomba, Claudia ; De Grazia, Simona ; Giammanco, Giovanni ; Martella, Vito. / Surveillance of human astrovirus circulation in Italy 2002-2005: emergence of lineage 2c strains. In: Clinical Microbiology and Infection. 2011 ; Vol. 17. pagg. 97-101.
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abstract = "By screening faecal samples collected over four consecutive years (2002-2005) from hospitalized children with diarrhoea in Palermo, Italy, astroviruses (HAstVs) were detected in 3.95{\%} of the patients. The predominant type circulating was HAstV-1 but, in 2002, only HAstV-2 and -4 were identified. Interestingly, the HAstVs-2 detected appeared to be consistently different in 5' end of their open reading frame 2 from the previously described subtypes. These novel type 2 strains were included in a new 2c lineage based on the phylogenetic analysis and the presence of nine peculiar substitutions.",
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T1 - Surveillance of human astrovirus circulation in Italy 2002-2005: emergence of lineage 2c strains

AU - Platia, Maria Angela

AU - Colomba, Claudia

AU - De Grazia, Simona

AU - Giammanco, Giovanni

AU - Martella, Vito

PY - 2011

Y1 - 2011

N2 - By screening faecal samples collected over four consecutive years (2002-2005) from hospitalized children with diarrhoea in Palermo, Italy, astroviruses (HAstVs) were detected in 3.95% of the patients. The predominant type circulating was HAstV-1 but, in 2002, only HAstV-2 and -4 were identified. Interestingly, the HAstVs-2 detected appeared to be consistently different in 5' end of their open reading frame 2 from the previously described subtypes. These novel type 2 strains were included in a new 2c lineage based on the phylogenetic analysis and the presence of nine peculiar substitutions.

AB - By screening faecal samples collected over four consecutive years (2002-2005) from hospitalized children with diarrhoea in Palermo, Italy, astroviruses (HAstVs) were detected in 3.95% of the patients. The predominant type circulating was HAstV-1 but, in 2002, only HAstV-2 and -4 were identified. Interestingly, the HAstVs-2 detected appeared to be consistently different in 5' end of their open reading frame 2 from the previously described subtypes. These novel type 2 strains were included in a new 2c lineage based on the phylogenetic analysis and the presence of nine peculiar substitutions.

KW - Astrovirus

KW - Italy

KW - gastroenteritis

KW - genotyping

KW - sequence analysis

UR - http://hdl.handle.net/10447/52744

M3 - Article

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SP - 97

EP - 101

JO - Clinical Microbiology and Infection

JF - Clinical Microbiology and Infection

SN - 1198-743X

ER -

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