Surveillance of human astrovirus circulation in Italy 2002-2005: emergence of lineage 2c strains

Giovanni Giammanco; Simona De Grazia; Claudia Colomba; Maria Angela Platia; Vito Martella

Surveillance of human astrovirus circulation in Italy 2002-2005: emergence of lineage 2c strains

Giovanni Giammanco, Simona De Grazia, Claudia Colomba, Maria Angela Platia, Vito Martella

Promozione della Salute, Materno-Infantile, di Medicina Interna e Specialistica di Eccellenza “G. D’Alessandro”

Risultato della ricerca: Article › peer review

27 Citazioni (Scopus)

Abstract

By screening faecal samples collected over four consecutive years (2002-2005) from hospitalized children with diarrhoea in Palermo, Italy, astroviruses (HAstVs) were detected in 3.95% of the patients. The predominant type circulating was HAstV-1 but, in 2002, only HAstV-2 and -4 were identified. Interestingly, the HAstVs-2 detected appeared to be consistently different in 5' end of their open reading frame 2 from the previously described subtypes. These novel type 2 strains were included in a new 2c lineage based on the phylogenetic analysis and the presence of nine peculiar substitutions.

Lingua originale	English
pagine (da-a)	97-101
Numero di pagine	5
Rivista	Clinical Microbiology and Infection
Volume	17
Stato di pubblicazione	Published - 2011

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Infectious Diseases

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title = "Surveillance of human astrovirus circulation in Italy 2002-2005: emergence of lineage 2c strains",

abstract = "By screening faecal samples collected over four consecutive years (2002-2005) from hospitalized children with diarrhoea in Palermo, Italy, astroviruses (HAstVs) were detected in 3.95% of the patients. The predominant type circulating was HAstV-1 but, in 2002, only HAstV-2 and -4 were identified. Interestingly, the HAstVs-2 detected appeared to be consistently different in 5' end of their open reading frame 2 from the previously described subtypes. These novel type 2 strains were included in a new 2c lineage based on the phylogenetic analysis and the presence of nine peculiar substitutions.",

keywords = "Astrovirus, Italy, gastroenteritis, genotyping, sequence analysis, Astrovirus, Italy, gastroenteritis, genotyping, sequence analysis",

author = "Giovanni Giammanco and {De Grazia}, Simona and Claudia Colomba and Platia, {Maria Angela} and Vito Martella",

year = "2011",

language = "English",

volume = "17",

pages = "97--101",

journal = "Clinical Microbiology and Infection",

issn = "1198-743X",

publisher = "Elsevier Limited",

}

TY - JOUR

T1 - Surveillance of human astrovirus circulation in Italy 2002-2005: emergence of lineage 2c strains

AU - Giammanco, Giovanni

AU - De Grazia, Simona

AU - Colomba, Claudia

AU - Platia, Maria Angela

AU - Martella, Vito

PY - 2011

Y1 - 2011

N2 - By screening faecal samples collected over four consecutive years (2002-2005) from hospitalized children with diarrhoea in Palermo, Italy, astroviruses (HAstVs) were detected in 3.95% of the patients. The predominant type circulating was HAstV-1 but, in 2002, only HAstV-2 and -4 were identified. Interestingly, the HAstVs-2 detected appeared to be consistently different in 5' end of their open reading frame 2 from the previously described subtypes. These novel type 2 strains were included in a new 2c lineage based on the phylogenetic analysis and the presence of nine peculiar substitutions.

AB - By screening faecal samples collected over four consecutive years (2002-2005) from hospitalized children with diarrhoea in Palermo, Italy, astroviruses (HAstVs) were detected in 3.95% of the patients. The predominant type circulating was HAstV-1 but, in 2002, only HAstV-2 and -4 were identified. Interestingly, the HAstVs-2 detected appeared to be consistently different in 5' end of their open reading frame 2 from the previously described subtypes. These novel type 2 strains were included in a new 2c lineage based on the phylogenetic analysis and the presence of nine peculiar substitutions.

KW - Astrovirus

KW - Italy

KW - gastroenteritis

KW - genotyping

KW - sequence analysis

KW - Astrovirus

KW - Italy

KW - gastroenteritis

KW - genotyping

KW - sequence analysis

UR - http://hdl.handle.net/10447/52744

M3 - Article

VL - 17

SP - 97

EP - 101

JO - Clinical Microbiology and Infection

JF - Clinical Microbiology and Infection

SN - 1198-743X

ER -