Surgical management of pleomorphic adenoma of parotid gland inelderly patients: Role of morphological features

Francesco Antonio Salzano, Gaetano Motta, Giovanni Salzano, Aldo Rocca, Giovanni Dell'Aversana Orabona, Giovanni Dell'Aversana Orabona, Bruno Amato, Pasquale Piombino, Domenico Tafuri, Stefania Montagnani, Domenico Testa, Germano Guerra

Risultato della ricerca: Article

15 Citazioni (Scopus)

Abstract

The neoplasms of the salivary glands account for 2% of head and neck tumors and the most commonform is the pleomorphic adenoma (PA). Parotid gland is affected from 80% to 90% of cases. In elderly thesetumors occur mostly in females. These benign tumors are composed of epithelial and myoepithelial cellsthat are arranged with various morphological patterns and subtypes. The classification of these tumors isalso based on the amount and nature of the stroma. In literature there is an almost complete consensusthat, in the major salivary glands, PAs are enclosed by a layer of fibrous tissue often called “capsule” butthere is disagreement about the form, extension and thickness of this layer. The treatment is surgical andthere are two main different surgical approaches: an enucleation (local dissection) or so-called subtotalsuperficial parotidectomy and lateral or superficial total parotidectomy. Histopathological characteristicsof PAs especially of capsular alterations such as thin capsule areas, capsule-free regions, capsule penetration,satellite nodules and pseudopodia in the different subtypes are important for the choice ofsurgical treatment and the first explanation for tumor recurrence. In our study we describe a morphologicalfeatures of 84 cases of pleomorphic adenoma of parotid gland from elderly patients treated by asurgical “enucleation like” method called nucleoresection.
Lingua originaleEnglish
Numero di pagine5
RivistaInternational Journal of Surgery
Volume12
Stato di pubblicazionePublished - 2014

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Pleomorphic Adenoma
Parotid Gland
Capsules
Neoplasms
Salivary Gland Neoplasms
Pseudopodia
Salivary Glands
Dissection
Neck
Head
Recurrence
Therapeutics

All Science Journal Classification (ASJC) codes

  • Surgery

Cita questo

Salzano, F. A., Motta, G., Salzano, G., Rocca, A., Dell'Aversana Orabona, G., Dell'Aversana Orabona, G., ... Guerra, G. (2014). Surgical management of pleomorphic adenoma of parotid gland inelderly patients: Role of morphological features. International Journal of Surgery, 12.

Surgical management of pleomorphic adenoma of parotid gland inelderly patients: Role of morphological features. / Salzano, Francesco Antonio; Motta, Gaetano; Salzano, Giovanni; Rocca, Aldo; Dell'Aversana Orabona, Giovanni; Dell'Aversana Orabona, Giovanni; Amato, Bruno; Piombino, Pasquale; Tafuri, Domenico; Montagnani, Stefania; Testa, Domenico; Guerra, Germano.

In: International Journal of Surgery, Vol. 12, 2014.

Risultato della ricerca: Article

Salzano, FA, Motta, G, Salzano, G, Rocca, A, Dell'Aversana Orabona, G, Dell'Aversana Orabona, G, Amato, B, Piombino, P, Tafuri, D, Montagnani, S, Testa, D & Guerra, G 2014, 'Surgical management of pleomorphic adenoma of parotid gland inelderly patients: Role of morphological features', International Journal of Surgery, vol. 12.
Salzano, Francesco Antonio ; Motta, Gaetano ; Salzano, Giovanni ; Rocca, Aldo ; Dell'Aversana Orabona, Giovanni ; Dell'Aversana Orabona, Giovanni ; Amato, Bruno ; Piombino, Pasquale ; Tafuri, Domenico ; Montagnani, Stefania ; Testa, Domenico ; Guerra, Germano. / Surgical management of pleomorphic adenoma of parotid gland inelderly patients: Role of morphological features. In: International Journal of Surgery. 2014 ; Vol. 12.
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abstract = "The neoplasms of the salivary glands account for 2{\%} of head and neck tumors and the most commonform is the pleomorphic adenoma (PA). Parotid gland is affected from 80{\%} to 90{\%} of cases. In elderly thesetumors occur mostly in females. These benign tumors are composed of epithelial and myoepithelial cellsthat are arranged with various morphological patterns and subtypes. The classification of these tumors isalso based on the amount and nature of the stroma. In literature there is an almost complete consensusthat, in the major salivary glands, PAs are enclosed by a layer of fibrous tissue often called “capsule” butthere is disagreement about the form, extension and thickness of this layer. The treatment is surgical andthere are two main different surgical approaches: an enucleation (local dissection) or so-called subtotalsuperficial parotidectomy and lateral or superficial total parotidectomy. Histopathological characteristicsof PAs especially of capsular alterations such as thin capsule areas, capsule-free regions, capsule penetration,satellite nodules and pseudopodia in the different subtypes are important for the choice ofsurgical treatment and the first explanation for tumor recurrence. In our study we describe a morphologicalfeatures of 84 cases of pleomorphic adenoma of parotid gland from elderly patients treated by asurgical “enucleation like” method called nucleoresection.",
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AU - Motta, Gaetano

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AU - Rocca, Aldo

AU - Dell'Aversana Orabona, Giovanni

AU - Dell'Aversana Orabona, Giovanni

AU - Amato, Bruno

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AU - Tafuri, Domenico

AU - Montagnani, Stefania

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AU - Guerra, Germano

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AB - The neoplasms of the salivary glands account for 2% of head and neck tumors and the most commonform is the pleomorphic adenoma (PA). Parotid gland is affected from 80% to 90% of cases. In elderly thesetumors occur mostly in females. These benign tumors are composed of epithelial and myoepithelial cellsthat are arranged with various morphological patterns and subtypes. The classification of these tumors isalso based on the amount and nature of the stroma. In literature there is an almost complete consensusthat, in the major salivary glands, PAs are enclosed by a layer of fibrous tissue often called “capsule” butthere is disagreement about the form, extension and thickness of this layer. The treatment is surgical andthere are two main different surgical approaches: an enucleation (local dissection) or so-called subtotalsuperficial parotidectomy and lateral or superficial total parotidectomy. Histopathological characteristicsof PAs especially of capsular alterations such as thin capsule areas, capsule-free regions, capsule penetration,satellite nodules and pseudopodia in the different subtypes are important for the choice ofsurgical treatment and the first explanation for tumor recurrence. In our study we describe a morphologicalfeatures of 84 cases of pleomorphic adenoma of parotid gland from elderly patients treated by asurgical “enucleation like” method called nucleoresection.

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