TY - JOUR
T1 - Stereoselective aldol reaction catalyzed by a highly recyclable polystyrene supported substituted prolinamide catalyst
AU - Gruttadauria, Michelangelo
AU - Noto, Renato
AU - Mossuto Marculescu, Adriana
AU - Salvo, Anna Maria Pia
AU - Giacalone, Francesco
PY - 2009
Y1 - 2009
N2 - Polystyrene supported substituted prolinamide was used as catalyst in the aldol reaction betweencyclohexanone or acetone and several substituted benzaldehydes in chloroform/water. Thiscatalyst afforded aldol products in high yields and stereoselectivities, especially in the case ofreactions performed with acetone. The catalyst was easily recovered by filtration and reused,after regeneration with formic acid, up to 22 times.
AB - Polystyrene supported substituted prolinamide was used as catalyst in the aldol reaction betweencyclohexanone or acetone and several substituted benzaldehydes in chloroform/water. Thiscatalyst afforded aldol products in high yields and stereoselectivities, especially in the case ofreactions performed with acetone. The catalyst was easily recovered by filtration and reused,after regeneration with formic acid, up to 22 times.
KW - aldol reaction
KW - organocatalysis
KW - polystyrene
KW - proline
KW - aldol reaction
KW - organocatalysis
KW - polystyrene
KW - proline
UR - http://hdl.handle.net/10447/37192
M3 - Article
VL - viii
SP - 5
EP - 15
JO - Arkivoc
JF - Arkivoc
SN - 1551-7004
ER -