Sperm DNA fragmentation: An early and reliable marker of air pollution

Maria Carmela Roccheri, Giosue' Lo Bosco, Liana Bosco, Chiara Martino, Rosanna Chiappetta, Salvatore Raimondo, Tiziana Notari, Luigi Montano, Laura Carrillo, Giosuè Lo Bosco, Antonino Guglielmino, Giovanni Ruvolo, Domenico Carone

Risultato della ricerca: Articlepeer review

23 Citazioni (Scopus)


Environmental factors could have a key role in the continuous and remarkable decline of sperm quality observed in the last decades. This study compared the seminal parameters and sperm DFI in men living in areas with different levels of air pollution. Results demonstrate that both steel plants workers and patients living in a high polluted area show a mean percentage of sperm DNA fragmentation above 30%, highlighting a clear sperm damage. In this work, two different techniques were used to measure sperm DNA damage in patientsâ groups, finding in both cases a high sperm DFI in patients living in polluted areas. We candidate sperm DNA fragmentation as a valuable early marker of the presence and harmful effects of pollution. We suggest that sperm DNA evaluation could be both an indicator of individual health and reproductive capacity, and a suitable datum to connect the surrounding environment with its effects.
Lingua originaleEnglish
pagine (da-a)243-249
Numero di pagine7
RivistaEnvironmental Toxicology and Pharmacology
Stato di pubblicazionePublished - 2018

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.3000.3004???
  • ???subjectarea.asjc.2300.2307???


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