Speciation of chitosan-phosphate and chitosan-nucleotide systems in an NaCl aqueous solution

Antonio Gianguzza, Daniela Piazzese, Silvio Sammartano, Concetta De Stefano

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2 Citazioni (Scopus)

Abstract

The speciation of chitosan (310 kDa) with organic (adenosine 5′-monophosphate, AMP, and adenosine 5′-triphosphate, ATP), and inorganic phosphorus containing ligands (phosphate and pyrophosphate) was investigated in NaCl aqueous solutions at I = 0.1 mol L−1 and T = 25°C. For all the systems, the investigated results obtained gave evidence for the formation of (chitosan)LHi complex species (L = nucleotides, phosphate and pyrophosphate; i = 1 to 4, but for AMP, i = 1 to 3). The stability data of complex species were used to calculate the sequestering ability of chitosan towards phosphorus compounds considered here, expressed as pL50 i.e., −log(total chitosan concentration) necessary to bind 50% of ligand. The pL50 values, calculated at different pH values, show quite a good sequestering ability of chitosan towards phosphorus compounds, in particular for the ones having higher negative charge, such as pyrophosphate and ATP.
Lingua originaleEnglish
pagine (da-a)99-107
Numero di pagine9
RivistaChemical Speciation and Bioavailability
Volume22
Stato di pubblicazionePublished - 2010

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Chitosan
Nucleotides
Phosphates
Adenosine Monophosphate
Phosphorus Compounds
Phosphorus compounds
Adenosine Triphosphate
Adenosinetriphosphate
Adenosine
Ligands
Phosphorus
diphosphoric acid

All Science Journal Classification (ASJC) codes

  • Chemical Health and Safety
  • Toxicology
  • Health, Toxicology and Mutagenesis

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title = "Speciation of chitosan-phosphate and chitosan-nucleotide systems in an NaCl aqueous solution",
abstract = "The speciation of chitosan (310 kDa) with organic (adenosine 5′-monophosphate, AMP, and adenosine 5′-triphosphate, ATP), and inorganic phosphorus containing ligands (phosphate and pyrophosphate) was investigated in NaCl aqueous solutions at I = 0.1 mol L−1 and T = 25°C. For all the systems, the investigated results obtained gave evidence for the formation of (chitosan)LHi complex species (L = nucleotides, phosphate and pyrophosphate; i = 1 to 4, but for AMP, i = 1 to 3). The stability data of complex species were used to calculate the sequestering ability of chitosan towards phosphorus compounds considered here, expressed as pL50 i.e., −log(total chitosan concentration) necessary to bind 50{\%} of ligand. The pL50 values, calculated at different pH values, show quite a good sequestering ability of chitosan towards phosphorus compounds, in particular for the ones having higher negative charge, such as pyrophosphate and ATP.",
keywords = "chitosan, nucleotides, phosphorus containing ligands, chemical speciation, polyammonium-phosphate interaction, polyammonium-nucleotide interaction",
author = "Antonio Gianguzza and Daniela Piazzese and Silvio Sammartano and {De Stefano}, Concetta",
year = "2010",
language = "English",
volume = "22",
pages = "99--107",
journal = "Chemical Speciation and Bioavailability",
issn = "0954-2299",
publisher = "Science Reviews Ltd",

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TY - JOUR

T1 - Speciation of chitosan-phosphate and chitosan-nucleotide systems in an NaCl aqueous solution

AU - Gianguzza, Antonio

AU - Piazzese, Daniela

AU - Sammartano, Silvio

AU - De Stefano, Concetta

PY - 2010

Y1 - 2010

N2 - The speciation of chitosan (310 kDa) with organic (adenosine 5′-monophosphate, AMP, and adenosine 5′-triphosphate, ATP), and inorganic phosphorus containing ligands (phosphate and pyrophosphate) was investigated in NaCl aqueous solutions at I = 0.1 mol L−1 and T = 25°C. For all the systems, the investigated results obtained gave evidence for the formation of (chitosan)LHi complex species (L = nucleotides, phosphate and pyrophosphate; i = 1 to 4, but for AMP, i = 1 to 3). The stability data of complex species were used to calculate the sequestering ability of chitosan towards phosphorus compounds considered here, expressed as pL50 i.e., −log(total chitosan concentration) necessary to bind 50% of ligand. The pL50 values, calculated at different pH values, show quite a good sequestering ability of chitosan towards phosphorus compounds, in particular for the ones having higher negative charge, such as pyrophosphate and ATP.

AB - The speciation of chitosan (310 kDa) with organic (adenosine 5′-monophosphate, AMP, and adenosine 5′-triphosphate, ATP), and inorganic phosphorus containing ligands (phosphate and pyrophosphate) was investigated in NaCl aqueous solutions at I = 0.1 mol L−1 and T = 25°C. For all the systems, the investigated results obtained gave evidence for the formation of (chitosan)LHi complex species (L = nucleotides, phosphate and pyrophosphate; i = 1 to 4, but for AMP, i = 1 to 3). The stability data of complex species were used to calculate the sequestering ability of chitosan towards phosphorus compounds considered here, expressed as pL50 i.e., −log(total chitosan concentration) necessary to bind 50% of ligand. The pL50 values, calculated at different pH values, show quite a good sequestering ability of chitosan towards phosphorus compounds, in particular for the ones having higher negative charge, such as pyrophosphate and ATP.

KW - chitosan, nucleotides, phosphorus containing ligands, chemical speciation, polyammonium-phosphate interaction, polyammonium-nucleotide interaction

UR - http://hdl.handle.net/10447/50380

M3 - Article

VL - 22

SP - 99

EP - 107

JO - Chemical Speciation and Bioavailability

JF - Chemical Speciation and Bioavailability

SN - 0954-2299

ER -