Sleep apnea risk in subjects with asthma with or without comorbid rhinitis

Nicola Scichilone, Ilaria Baiardini, Francesco Fanfulla, Fulvio Braido, Donato Lacedonia, Giorgia Molinengo, Giorgio W. Canonica, Fabrizio M. Facchini

Risultato della ricerca: Article

13 Citazioni (Scopus)

Abstract

BACKGROUND: As many as 80% of patients with asthma suffer from allergic rhinitis (AR), and rhinitis symptoms are associated with sleep complaints The aim of this cross-sectional study was to assess the prevalence of obstructive sleep apnea syndrome risk in patients with asthma and to explore the association between comorbid rhinitis and obstructive sleep apnea syndrome risk. METHODS: Subjects with asthma were recruited by general practitioners during a control visit. Physicians compiled a questionnaire that assessed the presence of AR according to ARIA (Allergic Rhinitis and Its Impact on Asthma) guidelines and factors influencing the risk of obstructive sleep apnea syndrome (gastroesophageal reflux disease, obesity, smoking). Subjects completed a questionnaire evaluating the presence and severity of AR and the STOP-BANG questionnaire (snoring, tiredness during daytime, observed apnea, high blood pressure, body mass index, age, neck circumference, gender), a validated screening method to identify obstructive sleep apnea syndrome risk. Physicians were blinded to the subjects’ questionnaires, ensuring objectivity of the method. RESULTS: The analyses were conducted on 1,941 subjects (males 58%, mean age 48.2 ± 15.2 y): 740 with asthma alone and 1,201 with asthma and AR. STOP-BANG revealed that 52.6% of the subjects were at increased risk of obstructive sleep apnea syndrome: 47.3% of subjects with asthma alone and 55.9% of patients with asthma and AR. Rhinitis was associated with a 1.44 times higher odds ratio for having obstructive sleep apnea syndrome risk. Rhinitis duration and severity were associated with obstructive sleep apnea syndrome risk, although the latter deserved greater importance. The results showed that, once a correction for each of these factors was performed, subjects with AR with an odds ratio of 1.99 were reported to be at risk of obstructive sleep apnea syndrome. CONCLUSIONS: The probable increased risk of obstructive sleep apnea syndrome is associated with the concomitant presence of rhinitis, independent of obesity and other contributors to risk of obstructive sleep apnea syndrome.
Lingua originaleEnglish
pagine (da-a)1851-1856
Numero di pagine6
RivistaRespiratory Care
Volume59
Stato di pubblicazionePublished - 2014

Fingerprint

Sleep Apnea Syndromes
Obstructive Sleep Apnea
Rhinitis
Asthma
Obesity
Odds Ratio
Physicians
Snoring
Apnea
Gastroesophageal Reflux
Allergic Rhinitis
General Practitioners
Sleep
Body Mass Index
Neck
Cross-Sectional Studies
Smoking
Guidelines
Hypertension
Surveys and Questionnaires

All Science Journal Classification (ASJC) codes

  • Pulmonary and Respiratory Medicine
  • Critical Care and Intensive Care Medicine

Cita questo

Scichilone, N., Baiardini, I., Fanfulla, F., Braido, F., Lacedonia, D., Molinengo, G., ... Facchini, F. M. (2014). Sleep apnea risk in subjects with asthma with or without comorbid rhinitis. Respiratory Care, 59, 1851-1856.

Sleep apnea risk in subjects with asthma with or without comorbid rhinitis. / Scichilone, Nicola; Baiardini, Ilaria; Fanfulla, Francesco; Braido, Fulvio; Lacedonia, Donato; Molinengo, Giorgia; Canonica, Giorgio W.; Facchini, Fabrizio M.

In: Respiratory Care, Vol. 59, 2014, pag. 1851-1856.

Risultato della ricerca: Article

Scichilone, N, Baiardini, I, Fanfulla, F, Braido, F, Lacedonia, D, Molinengo, G, Canonica, GW & Facchini, FM 2014, 'Sleep apnea risk in subjects with asthma with or without comorbid rhinitis', Respiratory Care, vol. 59, pagg. 1851-1856.
Scichilone N, Baiardini I, Fanfulla F, Braido F, Lacedonia D, Molinengo G e altri. Sleep apnea risk in subjects with asthma with or without comorbid rhinitis. Respiratory Care. 2014;59:1851-1856.
Scichilone, Nicola ; Baiardini, Ilaria ; Fanfulla, Francesco ; Braido, Fulvio ; Lacedonia, Donato ; Molinengo, Giorgia ; Canonica, Giorgio W. ; Facchini, Fabrizio M. / Sleep apnea risk in subjects with asthma with or without comorbid rhinitis. In: Respiratory Care. 2014 ; Vol. 59. pagg. 1851-1856.
@article{afd4c1910afc4465ad13de340426040a,
title = "Sleep apnea risk in subjects with asthma with or without comorbid rhinitis",
abstract = "BACKGROUND: As many as 80{\%} of patients with asthma suffer from allergic rhinitis (AR), and rhinitis symptoms are associated with sleep complaints The aim of this cross-sectional study was to assess the prevalence of obstructive sleep apnea syndrome risk in patients with asthma and to explore the association between comorbid rhinitis and obstructive sleep apnea syndrome risk. METHODS: Subjects with asthma were recruited by general practitioners during a control visit. Physicians compiled a questionnaire that assessed the presence of AR according to ARIA (Allergic Rhinitis and Its Impact on Asthma) guidelines and factors influencing the risk of obstructive sleep apnea syndrome (gastroesophageal reflux disease, obesity, smoking). Subjects completed a questionnaire evaluating the presence and severity of AR and the STOP-BANG questionnaire (snoring, tiredness during daytime, observed apnea, high blood pressure, body mass index, age, neck circumference, gender), a validated screening method to identify obstructive sleep apnea syndrome risk. Physicians were blinded to the subjects’ questionnaires, ensuring objectivity of the method. RESULTS: The analyses were conducted on 1,941 subjects (males 58{\%}, mean age 48.2 ± 15.2 y): 740 with asthma alone and 1,201 with asthma and AR. STOP-BANG revealed that 52.6{\%} of the subjects were at increased risk of obstructive sleep apnea syndrome: 47.3{\%} of subjects with asthma alone and 55.9{\%} of patients with asthma and AR. Rhinitis was associated with a 1.44 times higher odds ratio for having obstructive sleep apnea syndrome risk. Rhinitis duration and severity were associated with obstructive sleep apnea syndrome risk, although the latter deserved greater importance. The results showed that, once a correction for each of these factors was performed, subjects with AR with an odds ratio of 1.99 were reported to be at risk of obstructive sleep apnea syndrome. CONCLUSIONS: The probable increased risk of obstructive sleep apnea syndrome is associated with the concomitant presence of rhinitis, independent of obesity and other contributors to risk of obstructive sleep apnea syndrome.",
keywords = "Allergic rhinitis; Asthma; Obstructive sleep apnea syndrome; Risk; Sleep apnea; STOP-BANG; Adult; Asthma; Comorbidity; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Prevalence; Rhinitis, Allergic; Risk Factors; Severity of Illness Index; Sleep Apnea, Obstructive; Surveys and Questionnaires; Time Factors; Pulmonary and Respiratory Medicine; Critical Care and Intensive Care Medicine; Medicine (all)",
author = "Nicola Scichilone and Ilaria Baiardini and Francesco Fanfulla and Fulvio Braido and Donato Lacedonia and Giorgia Molinengo and Canonica, {Giorgio W.} and Facchini, {Fabrizio M.}",
year = "2014",
language = "English",
volume = "59",
pages = "1851--1856",
journal = "Respiratory Care",
issn = "0020-1324",
publisher = "Daedalus Enterprises Inc.",

}

TY - JOUR

T1 - Sleep apnea risk in subjects with asthma with or without comorbid rhinitis

AU - Scichilone, Nicola

AU - Baiardini, Ilaria

AU - Fanfulla, Francesco

AU - Braido, Fulvio

AU - Lacedonia, Donato

AU - Molinengo, Giorgia

AU - Canonica, Giorgio W.

AU - Facchini, Fabrizio M.

PY - 2014

Y1 - 2014

N2 - BACKGROUND: As many as 80% of patients with asthma suffer from allergic rhinitis (AR), and rhinitis symptoms are associated with sleep complaints The aim of this cross-sectional study was to assess the prevalence of obstructive sleep apnea syndrome risk in patients with asthma and to explore the association between comorbid rhinitis and obstructive sleep apnea syndrome risk. METHODS: Subjects with asthma were recruited by general practitioners during a control visit. Physicians compiled a questionnaire that assessed the presence of AR according to ARIA (Allergic Rhinitis and Its Impact on Asthma) guidelines and factors influencing the risk of obstructive sleep apnea syndrome (gastroesophageal reflux disease, obesity, smoking). Subjects completed a questionnaire evaluating the presence and severity of AR and the STOP-BANG questionnaire (snoring, tiredness during daytime, observed apnea, high blood pressure, body mass index, age, neck circumference, gender), a validated screening method to identify obstructive sleep apnea syndrome risk. Physicians were blinded to the subjects’ questionnaires, ensuring objectivity of the method. RESULTS: The analyses were conducted on 1,941 subjects (males 58%, mean age 48.2 ± 15.2 y): 740 with asthma alone and 1,201 with asthma and AR. STOP-BANG revealed that 52.6% of the subjects were at increased risk of obstructive sleep apnea syndrome: 47.3% of subjects with asthma alone and 55.9% of patients with asthma and AR. Rhinitis was associated with a 1.44 times higher odds ratio for having obstructive sleep apnea syndrome risk. Rhinitis duration and severity were associated with obstructive sleep apnea syndrome risk, although the latter deserved greater importance. The results showed that, once a correction for each of these factors was performed, subjects with AR with an odds ratio of 1.99 were reported to be at risk of obstructive sleep apnea syndrome. CONCLUSIONS: The probable increased risk of obstructive sleep apnea syndrome is associated with the concomitant presence of rhinitis, independent of obesity and other contributors to risk of obstructive sleep apnea syndrome.

AB - BACKGROUND: As many as 80% of patients with asthma suffer from allergic rhinitis (AR), and rhinitis symptoms are associated with sleep complaints The aim of this cross-sectional study was to assess the prevalence of obstructive sleep apnea syndrome risk in patients with asthma and to explore the association between comorbid rhinitis and obstructive sleep apnea syndrome risk. METHODS: Subjects with asthma were recruited by general practitioners during a control visit. Physicians compiled a questionnaire that assessed the presence of AR according to ARIA (Allergic Rhinitis and Its Impact on Asthma) guidelines and factors influencing the risk of obstructive sleep apnea syndrome (gastroesophageal reflux disease, obesity, smoking). Subjects completed a questionnaire evaluating the presence and severity of AR and the STOP-BANG questionnaire (snoring, tiredness during daytime, observed apnea, high blood pressure, body mass index, age, neck circumference, gender), a validated screening method to identify obstructive sleep apnea syndrome risk. Physicians were blinded to the subjects’ questionnaires, ensuring objectivity of the method. RESULTS: The analyses were conducted on 1,941 subjects (males 58%, mean age 48.2 ± 15.2 y): 740 with asthma alone and 1,201 with asthma and AR. STOP-BANG revealed that 52.6% of the subjects were at increased risk of obstructive sleep apnea syndrome: 47.3% of subjects with asthma alone and 55.9% of patients with asthma and AR. Rhinitis was associated with a 1.44 times higher odds ratio for having obstructive sleep apnea syndrome risk. Rhinitis duration and severity were associated with obstructive sleep apnea syndrome risk, although the latter deserved greater importance. The results showed that, once a correction for each of these factors was performed, subjects with AR with an odds ratio of 1.99 were reported to be at risk of obstructive sleep apnea syndrome. CONCLUSIONS: The probable increased risk of obstructive sleep apnea syndrome is associated with the concomitant presence of rhinitis, independent of obesity and other contributors to risk of obstructive sleep apnea syndrome.

KW - Allergic rhinitis; Asthma; Obstructive sleep apnea syndrome; Risk; Sleep apnea; STOP-BANG; Adult; Asthma; Comorbidity; Cross-Sectional Studies; Female; Humans; Male; Middle Aged; Prevalence; Rhinitis, Allergic; Risk Factors; Severity of Illness Index; Sle

UR - http://hdl.handle.net/10447/214443

UR - http://rc.rcjournal.com/content/59/12/1851.full.pdf

M3 - Article

VL - 59

SP - 1851

EP - 1856

JO - Respiratory Care

JF - Respiratory Care

SN - 0020-1324

ER -