Si photomultipliers for bio-sensing applications

Alessandro Busacca, Maria Francesca Santangelo, Salvatore A. Lombardo, Emanuele Luigi Sciuto, Maria Francesca Santangelo, Salvatore Petralia, Sabrina Conoci, Sebania Libertino, Salvatore Petralia

Risultato della ricerca: Articlepeer review

21 Citazioni (Scopus)

Abstract

In this paper, silicon photomultipliers (SiPM) are proposed as optical detectors for bio sensing. Optical transduction is the most used detection mechanism in many biosensor applications, such as DNA microarray and real-time polymerase chain reaction. The performances of a 25 pixels device used for both applications are studied. The results confirm that the SiPM is more sensitive than the traditionally employed detectors. In fact, it is able to experimentally detect 1 nM and 100 fM of fluorophore concentrations in dried samples and solutions, respectively. We present and discuss in details the detector configuration and its characterization as fluorescence detector for bio sensing.
Lingua originaleEnglish
pagine (da-a)335-341
Numero di pagine7
RivistaIEEE JOURNAL OF SELECTED TOPICS IN QUANTUM ELECTRONICS
Volume22
Stato di pubblicazionePublished - 2016

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.2200.2208???

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