TY - JOUR
T1 - Sex differences in obstructive sleep apnoea
AU - Bonsignore, Maria Rosaria
AU - Bonsignore, Maria
AU - Bonsignore, Maria R.
AU - Riha, Renata
AU - Riha, Renata L.
AU - Bonsignore, Maria R.
AU - Riha, Renata
AU - Riha, Renata L.
AU - Saaresranta, Tarja
PY - 2019
Y1 - 2019
N2 - Obstructive sleep apnoea (OSA) and obstructive sleep apnoea/hypopnoea syndrome (OSAHS) have long been considered predominantly male-related conditions. The clinical presentation of sleep disordered breathing in females differs from males and can vary with age and physiological status, e.g. menopause and pregnancy. Overall, females appear to be more symptomatic, with lower apnoea- hypopnoea index scores compared to males. Furthermore, they appear to have more prolonged partial upper airway obstruction, and may report insomnia as a symptom of OSAHS more frequently. As a consequence of these differences in clinical presentation, females with sleep disordered breathing are often underdiagnosed and undertreated compared to males. This review is aimed at discussing the epidemiology, clinical presentation, pathophysiology and hormonal and metabolic differences in females who present with OSA/OSAHS in comparison to males.
AB - Obstructive sleep apnoea (OSA) and obstructive sleep apnoea/hypopnoea syndrome (OSAHS) have long been considered predominantly male-related conditions. The clinical presentation of sleep disordered breathing in females differs from males and can vary with age and physiological status, e.g. menopause and pregnancy. Overall, females appear to be more symptomatic, with lower apnoea- hypopnoea index scores compared to males. Furthermore, they appear to have more prolonged partial upper airway obstruction, and may report insomnia as a symptom of OSAHS more frequently. As a consequence of these differences in clinical presentation, females with sleep disordered breathing are often underdiagnosed and undertreated compared to males. This review is aimed at discussing the epidemiology, clinical presentation, pathophysiology and hormonal and metabolic differences in females who present with OSA/OSAHS in comparison to males.
UR - http://hdl.handle.net/10447/400383
UR - https://err.ersjournals.com/content/errev/28/154/190030.full.pdf
M3 - Article
VL - 28
JO - European Respiratory Review
JF - European Respiratory Review
SN - 0905-9180
ER -