Several 1,3-thiazolidin-4-ones bearing a 2,6-dihalophenyl group at C-2 and a variously substituted phenyl ring at N-3 have beensynthesized and tested as anti-HIV agents. The results of the in vitro tests showed that some of them proved to be effective inhibitorsof HIV-1 replication.

Risultato della ricerca: Articlepeer review

Abstract

Several 1,3-thiazolidin-4-ones bearing a 2,6-dihalophenyl group at C-2 and a variously substituted phenyl ring at N-3 have beensynthesized and tested as anti-HIV agents. The results of the in vitro tests showed that some of them proved to be effective inhibitorsof HIV-1 replication.
Lingua originaleEnglish
pagine (da-a)115-120
Numero di pagine6
RivistaIL FARMACO
Volume58
Stato di pubblicazionePublished - 2003

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