Seroprevalence of Norovirus Genogroup IV antibodies among humans, Italy, 2010–2011

Giovanni Giammanco, Simona De Grazia, Chiara Ceci, Federica Di Profio, Fulvio Marsilio, Elisabetta Di Felice, Karin Bok, Ivano Massirio, Vito Martella, Canio Buonavoglia, Kim Y. Green, Eleonora Lorusso, Barbara Di Martino

Risultato della ricerca: Article

19 Citazioni (Scopus)

Abstract

Noroviruses (NoVs) of genogroup IV (GIV) (Alphatron-like) cause infections in humans and in carnivorous animals such as dogs and cats. We screened an age-stratified collection of serum samples from 535 humans in Italy, using virus-like particles of genotypes GIV.1, circulating in humans, and GIV.2, identified in animals, in ELISA, in order to investigate the prevalence of GIV NoV-specific IgG antibodies. Antibodies specific for both genotypes were detected, ranging from a prevalence of 6.6% to 44.8% for GIV.1 and from 6.8% to 15.1% for GIV.2 among different age groups. These data are consistent with a higher prevalence of GIV.1 strains in the human population. Analysis of antibodies against GIV.2 suggests zoonotic transmission of animal NoVs, likely attributable to interaction between humans and domestic pets. This finding, and recent documentation of human transmission of NoVs to dogs, indicate the possibility of an evolutionary relationship between human and animal NoVs.
Lingua originaleEnglish
pagine (da-a)1867-1871
Numero di pagine5
RivistaEmerging Infectious Diseases
Volume20
Stato di pubblicazionePublished - 2014

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Norovirus
Seroepidemiologic Studies
Italy
Genotype
Antibodies
Dogs
Pets
Zoonoses
Documentation
Virion
Cats
Age Groups
Immunoglobulin G
Enzyme-Linked Immunosorbent Assay
Infection
Serum
Population

All Science Journal Classification (ASJC) codes

  • Epidemiology
  • Microbiology (medical)
  • Infectious Diseases

Cita questo

Giammanco, G., De Grazia, S., Ceci, C., Di Profio, F., Marsilio, F., Felice, E. D., ... Martino, B. D. (2014). Seroprevalence of Norovirus Genogroup IV antibodies among humans, Italy, 2010–2011. Emerging Infectious Diseases, 20, 1867-1871.

Seroprevalence of Norovirus Genogroup IV antibodies among humans, Italy, 2010–2011. / Giammanco, Giovanni; De Grazia, Simona; Ceci, Chiara; Di Profio, Federica; Marsilio, Fulvio; Felice, Elisabetta Di; Bok, Karin; Massirio, Ivano; Martella, Vito; Buonavoglia, Canio; Green, Kim Y.; Lorusso, Eleonora; Martino, Barbara Di.

In: Emerging Infectious Diseases, Vol. 20, 2014, pag. 1867-1871.

Risultato della ricerca: Article

Giammanco, G, De Grazia, S, Ceci, C, Di Profio, F, Marsilio, F, Felice, ED, Bok, K, Massirio, I, Martella, V, Buonavoglia, C, Green, KY, Lorusso, E & Martino, BD 2014, 'Seroprevalence of Norovirus Genogroup IV antibodies among humans, Italy, 2010–2011', Emerging Infectious Diseases, vol. 20, pagg. 1867-1871.
Giammanco, Giovanni ; De Grazia, Simona ; Ceci, Chiara ; Di Profio, Federica ; Marsilio, Fulvio ; Felice, Elisabetta Di ; Bok, Karin ; Massirio, Ivano ; Martella, Vito ; Buonavoglia, Canio ; Green, Kim Y. ; Lorusso, Eleonora ; Martino, Barbara Di. / Seroprevalence of Norovirus Genogroup IV antibodies among humans, Italy, 2010–2011. In: Emerging Infectious Diseases. 2014 ; Vol. 20. pagg. 1867-1871.
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abstract = "Noroviruses (NoVs) of genogroup IV (GIV) (Alphatron-like) cause infections in humans and in carnivorous animals such as dogs and cats. We screened an age-stratified collection of serum samples from 535 humans in Italy, using virus-like particles of genotypes GIV.1, circulating in humans, and GIV.2, identified in animals, in ELISA, in order to investigate the prevalence of GIV NoV-specific IgG antibodies. Antibodies specific for both genotypes were detected, ranging from a prevalence of 6.6{\%} to 44.8{\%} for GIV.1 and from 6.8{\%} to 15.1{\%} for GIV.2 among different age groups. These data are consistent with a higher prevalence of GIV.1 strains in the human population. Analysis of antibodies against GIV.2 suggests zoonotic transmission of animal NoVs, likely attributable to interaction between humans and domestic pets. This finding, and recent documentation of human transmission of NoVs to dogs, indicate the possibility of an evolutionary relationship between human and animal NoVs.",
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AU - Giammanco, Giovanni

AU - De Grazia, Simona

AU - Ceci, Chiara

AU - Di Profio, Federica

AU - Marsilio, Fulvio

AU - Felice, Elisabetta Di

AU - Bok, Karin

AU - Massirio, Ivano

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AU - Buonavoglia, Canio

AU - Green, Kim Y.

AU - Lorusso, Eleonora

AU - Martino, Barbara Di

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N2 - Noroviruses (NoVs) of genogroup IV (GIV) (Alphatron-like) cause infections in humans and in carnivorous animals such as dogs and cats. We screened an age-stratified collection of serum samples from 535 humans in Italy, using virus-like particles of genotypes GIV.1, circulating in humans, and GIV.2, identified in animals, in ELISA, in order to investigate the prevalence of GIV NoV-specific IgG antibodies. Antibodies specific for both genotypes were detected, ranging from a prevalence of 6.6% to 44.8% for GIV.1 and from 6.8% to 15.1% for GIV.2 among different age groups. These data are consistent with a higher prevalence of GIV.1 strains in the human population. Analysis of antibodies against GIV.2 suggests zoonotic transmission of animal NoVs, likely attributable to interaction between humans and domestic pets. This finding, and recent documentation of human transmission of NoVs to dogs, indicate the possibility of an evolutionary relationship between human and animal NoVs.

AB - Noroviruses (NoVs) of genogroup IV (GIV) (Alphatron-like) cause infections in humans and in carnivorous animals such as dogs and cats. We screened an age-stratified collection of serum samples from 535 humans in Italy, using virus-like particles of genotypes GIV.1, circulating in humans, and GIV.2, identified in animals, in ELISA, in order to investigate the prevalence of GIV NoV-specific IgG antibodies. Antibodies specific for both genotypes were detected, ranging from a prevalence of 6.6% to 44.8% for GIV.1 and from 6.8% to 15.1% for GIV.2 among different age groups. These data are consistent with a higher prevalence of GIV.1 strains in the human population. Analysis of antibodies against GIV.2 suggests zoonotic transmission of animal NoVs, likely attributable to interaction between humans and domestic pets. This finding, and recent documentation of human transmission of NoVs to dogs, indicate the possibility of an evolutionary relationship between human and animal NoVs.

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