SENP1 activity sustains cancer stem cell in hypoxic HCC

Alice Conigliaro, Alice Conigliaro, Maurizio Parola, Marco Tripodi

Risultato della ricerca: Review article

3 Citazioni (Scopus)

Abstract

Hepatocellular carcinoma (HCC) represents the fifth most common cancer and the third leading cause of cancer mortality worldwide, with a minority of patients surviving at 5 years from diagnosis, despite treatment. HCC usually develops in conditions of chronic liver disease (CLD), mostly on the background of a cirrhotic liver, with liver transplantation at present being the only treatment strategy to cure both HCC and the specific CLD.
Lingua originaleEnglish
pagine (da-a)2051-
Numero di pagine3
RivistaGut
Volume66
Stato di pubblicazionePublished - 2017

All Science Journal Classification (ASJC) codes

  • Gastroenterology

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