Screening of antioxidant potentials and bioactive properties of the extracts obtained from two Centaurea L. species (C. kroumirensis coss. and C. sicula L. subsp sicula)

Andrea Santulli, Concetta Maria Messina, Hatem Dhaouadi, Abdelkarim Mahdhi, Nedra Dhouibi, Andrea Santulli, Rosaria Arena, Simona Manuguerra

Risultato della ricerca: Articlepeer review

1 Citazioni (Scopus)

Abstract

Herbal medicines, dietary supplements, or infusions with health promoting effects can note strong consumer demand. Hence, researchers and scientists have been increasingly focusing on the promotion of medicinal plants. In this respect, the present study has the evaluation of the biological properties of different extracts (hexane, chloroform, methanol, ultrasonic, essential oil, and supercritical) obtained from two Centaurea species (C. kroumirensis (Coss.) and C. sicula L. subsp sicula) as purpose. Antioxidative activities were assessed by in vitro assays including total phenolic content, free radical scavenging assay and ferric ion reducing power. Among the fourteen extracts examined, the highest total phenolic content (TPC) and antioxidant abilities were recorded in ultrasonic ethanol extracts of both Centaurea species. Additionally, these extracts exhibited a noticeable strong protective effect of the human skin fibroblast cell line (HS-68) that was exposed to oxidative stress induced by hydrogen peroxide. According to our results, the sonication with ethanol might be an ideal, rapid, and eco-friendly extraction method for obtaining a polyphenol-rich extract that exhibited high antioxidant activity. The results presented herein suggest that Centaurea species could be promoted as an antioxidant resource that could be exploited for the development of nutraceuticals or in pharmacology industry.
Lingua originaleEnglish
pagine (da-a)2267-
Numero di pagine13
RivistaAPPLIED SCIENCES
Volume10
Stato di pubblicazionePublished - 2020

All Science Journal Classification (ASJC) codes

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  • Instrumentation
  • ???subjectarea.asjc.2200.2200???
  • Process Chemistry and Technology
  • Computer Science Applications
  • Fluid Flow and Transfer Processes

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