Satisfaction with chronic obstructive pulmonary disease treatment: results from a multicenter, observational study

Nicola Scichilone, Lucia Simoni, Paolo Mimotti, Giuseppe Fiorentino, Antonella Marotta, Luigi Di Re, Giovanni Florio, Alida Benfante, Dejan Radovanovic, Roberto Piro, Laura Maugeri, Patrizia Lessi, Giacomo Forini, Laura Maugeri, Marco Contoli, Claudio Micheletto, Francesco Spannella, Erica Gini, Riccardo Sarzani, Rigoletta VincentiAlessandra Ori, Francesca Trevisan, Francesco Cavalli, Giovanni Fiori, Christian Amici, Patrizia Ruggiero, Silvia Garuti, Antonio Iannaccone, Fausta Alfano, Barbara Roncari, Francesca Trevisan, Carla Scognamillo, Fabio Ferri, Saide Sala, Giovanni Florio, Roberto Carbone, Rodolfo Riva, Alessandro Izzo, Christian A. Amici, Laura Maugeri, Biago Polla, Antonio Iannaccone, Stefano Viaggi, Claudio Micheletto, Laura Maugeri, Laura Maugeri, Rita Raccanelli, Roberto Tazza, Barbara Roncari, Maria Aliani, Paola Rogliani, Carlo Gulotta, Fabiano Di Marco, Angelo G. Corsico, Angelo Guido Corsico, Mauro Carone, Stefano Viaggi, Vincenzo Patella, Roberto Carbone, Fulvio Braido, Nicole Lanci, Pierachille Santus

Risultato della ricerca: Articlepeer review

5 Citazioni (Scopus)

Abstract

Background: Understanding the level of patients’ satisfaction with treatment and its determinants have the potential to impact therapeutic management and clinical outcome in chronic conditions such as chronic obstructive pulmonary disease (COPD). Methods: A national, multicenter, longitudinal, observational study of COPD from 20 Italian pulmonary centers to explore patients’ satisfaction to treatment [assessed by the Treatment Satisfaction Questionnaire, 9 items (TSQM-9)] and association with clinical parameters [including dyspnea score, COPD Assessment Test (CAT) score, exacerbation rate], adherence to treatment [Morisky Medication-Taking Adherence Scale (MMAS-4)], illness perception [evaluated by Brief Illness Perception Questionnaire (B-IPQ)] in a 1-year follow up. Results: A total of 401 COPD patients were enrolled [69.4% group B Global Initiative for COPD (GOLD), considering 366 patients with available GOLD 2017 classification at enrollment]. At enrollment, satisfaction with treatment was moderate, being TSQM-9 mean scores for effectiveness 64.2 [95% confidence interval (CI) 62.5–65.9], for convenience 75.8 (95% CI 74.2–77.3), and for global satisfaction 65.7 (95% CI 64.0–67.4). Global satisfaction was negatively associated with disease perception (β = −0.4709, p < 0.0001), and grade of dyspnea (β = −4.2564, p = 0.009). Satisfaction with treatment was lower in patients with poor compared with optimal adherence to treatment (β = −4.5608, p = 0.002). Changes in inhalation regimens during follow up did not modify the satisfaction with treatment. Conclusions: The results of this real-life study showed that the patients’ satisfaction with treatments is only moderate in COPD. A high grade of patients’ satisfaction is associated mainly with a low perception of the disease, high adherence to treatment and lower level of dyspnea. Trial Registration: Clinicaltrials.gov identifier: NCT02689492 The reviews of this paper are available via the supplemental material section.
Lingua originaleEnglish
pagine (da-a)1753466619888128-
Numero di pagine0
RivistaTherapeutic Advances in Respiratory Disease
Volume13
Stato di pubblicazionePublished - 2019

All Science Journal Classification (ASJC) codes

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