SARS-CoV-2 mRNA Vaccine Breakthrough Infections in Fully Vaccinated Healthcare Personnel: A Systematic Review

Claudio Costantino, Rosario Cunsolo, Helena C. Maltezou, Caterina Ledda, Giuseppe Motta, Giuseppe Liberti, Patrizia Stracquadanio, Venerando Rapisarda

Risultato della ricerca: Articlepeer review

10 Citazioni (Scopus)

Abstract

The number of people vaccinated against COVID-19 increases worldwide every day; however, it is important to study the risk of breakthrough infections in vaccinated individuals at high risk of exposure such as healthcare personnel (HCP). A systematic literature review (SLR) applying the PRISMA declaration and the PECOS format using the following entry terms was used: “Health Personnel OR Healthcare Worker OR Healthcare Provider OR Healthcare Personnel AND breakthrough OR infection after vaccine*”. The research was carried out utilizing the following databases: SCOPUS, PubMed, Embase, and Web of Sciences. An overall very low incidence of post-vaccination breakthrough infections was found, ranging from 0.011 to 0.001 (per 100 individuals at risk). Our findings further support the published high effectiveness rates of mRNA vaccines in preventing SARS-CoV-2 infections among fully vaccinated HCP. Additional studies are needed to define the duration of the vaccine-induced protection among HCP.
Lingua originaleEnglish
pagine (da-a)1-11
Numero di pagine11
RivistaTropical Medicine and Infectious Disease
Volume7
Stato di pubblicazionePublished - 2022

All Science Journal Classification (ASJC) codes

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  • ???subjectarea.asjc.2700.2739???
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